Vaccination may combat Clostridium difficile

UK - Whilst the life-threatening Clostridium difficile is not absolutely resistant to antibiotics, after an individual has been infected the bacteria often reappears.

Photo: Vaccination may combat Clostridium difficile

Vaccination against it is therefore seen as the possible answer, and now results from initial trials of one made by Acambis, a Cambridge-based biotech company, have encouraged its scientists to discuss involvement of the National Health Service (NHS) in tests in hospitals this year.
Rather than targeting the infection, this developing vaccine focuses on the toxins produced by a C. difficile infection. Trials on 200 patients indicate that the vaccine was effective at combating one of the major toxins in 100% of cases and a second major toxin in 75% of cases.
It is hoped that a course of three injections will provide long-lasting protection for over a decade.


More on the subject:
Read all latest stories

Related articles


COVID-19 disinfection

New insights into SARS-CoV-2 surface stability and temperature susceptibility

Surface disinfection has proved an effective method to control COVID-19 infection, as virologists from the Ruhr University Bochum (RUB) have shown. However, an effective disinfection strategy against…


Hardware and software solutions

Integrated OR and hygiene belong together

According to the German Federal Ministry of Health, 400,000 to 600,000 patients are diagnosed with hospital-acquired infections every year. The treatment of these nosocomial diseases is complex.…


Sterilising with VHP, EO or HPGP

Sterilisation study puts cleansing methods to the test

A new study from the USA highlights how low temperature sterilisation can jeopardise effective cleansing of medical tools and lead to transmission of dangerous bacteria to patients. Steam…