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While the coronavirus has dominated the field of infectiology since the start of the pandemic, this year’s ECCMID congress regains more diversity: Covid-19 is still an obvious mainstay, but management of antibiotic resistance and regulatory issues such as the upcoming IVDR make a return for the first hybrid edition of the event. Enjoy reading!

Article • Drug dose optimisation

Antibiotics: no more ‘dosing in the dark’

Finding the right antibiotic dose is akin to a Goldilocks problem: give too little, and the infection will persist; too much, and side-effects will override the benefits of the therapy. To get it “just right”, Prof Dr Birgit Koch talks about ...

News • Deep learning approach

'Curvy' bacteria as telltale sign of drug resistance?

Researchers find that drug-resistant bacteria can be distinguished from non-resistant bacteria based on structural changes evident in electron microscope images with high accuracy using deep learning.

Article • Impact of the new regulation

IVDR: Stop complaining, start contributing

The in vitro diagnostic regulation (IVDR) aims to make tests safer, more reliable, and sustainable. Unfortunately, it is also widely regarded a bureaucratic nightmare. At the ECCMID Day on Diagnostics, an expert proposed a more constructive approach.

Article • UHPLC-MS/MS analysis

Predicting Covid-19 infection severity with mass spec

Using mass spectrometry and chromatography techniques, UK researchers have developed an approach to predict infection severity among Covid-19 patients, as well as potential outcomes.

News • Global study finds increase in deaths

Why is Covid-19 more deadly on weekends?

A global analysis of nearly 6 million Covid-19 deaths finds an increase in mortality at weekends compared to weekdays. Bureaucratic and reporting delays alone do not explain this, researchers report.

News • Connection between genes and disease severity

E. coli: How does an intestinal germ become a pathogen?

In the human intestine, Escherichia coli is mostly harmless, but in certain conditions causes bladder infections and even sepsis - but why? Researchers went to the bottom of this transformation.

News • Bacterial protection strategy

Protective 'chain mail' of C.difficile revealed

A newly discovered structure of chain-mail may explain the success of C.difficile at defending itself against antibiotics and immune system molecules.

Collections

Article • Bacterial defense mechanism

Antibiotic resistance: a global threat to healthcare

Article • Covid-19

Coronavirus update

 

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