Radiotherapy for arthritis? Stem cells for spina bifida treatment? What seemed unthinkable just a few years ago is gradually becoming clinical reality. This newsletter highlights promising pioneering approaches that challenge established treatment paradigms. An evolutionary modelling study proposes sequential therapy switching to improve cancer cure rates, while an AI-powered electronic nose shows promise in detecting ovarian cancer. Additional topics include a surgical approach to Alzheimer's disease and advances in cardiac imaging. Enjoy reading!
Article • Beyond drugs and surgery
Radiation for joint pain? Study validates low-dose approach for knee osteoarthritis
The concept of using radiotherapy for osteoarthritis may seem counterintuitive for many clinicians. Yet a well-designed randomised controlled trial presented at the 2025 ASTRO Annual Meeting in San Francisco suggests that low-dose radiotherapy ...
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News • Treatment approachHow to improve cancer cure rates? “Kick it while it’s down”Although tumours may at first shrink under therapy, they often regrow or even become resistant. A new study suggests switching to a second treatment while the tumour is still responding to the first. |
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News • Combining stem cell therapy with surgerySpina bifida: in-utero stem cell treatment approach shows promiseCombining stem cell therapy with standard fetal surgery before birth is a safe and promising approach to treat myelomeningocele, a severe form of spina bifida, a new study has shown. |
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News • Biomarker-agnostic detectionElectronic nose uses AI to “smell” ovarian cancerUsing machine learning, researchers have trained an electronic nose to detect early signs of ovarian cancer in the blood. The method could eventually be used to find many different cancers. |
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News • New sequencing techniqueClassifying pediatric brain tumors with liquid biopsy and AIClues in the CSF: Researchers have developed the first high-precision method that can theoretically diagnose common brain tumors in children and adolescents without surgery. |
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News • At least 18 years of reduced riskCervical cancer: study confirms long-term protection from HPV vaccinationVaccination against human papillomavirus (HPV) reduces the risk of cervical cancer for at least 18 years, according to a new study. There were no signs of waning protection over time. |
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News • Lymphovenous bypassA surgical treatment for Alzheimer's disease?A small but growing body of evidence suggests that a minimally invasive surgical procedure called lymphovenous anastomosis (LVA) might be an effective treatment for Alzheimer's disease. |
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News • LLMs confirm delusionsMental illness and AI chatbots: a dangerous matchWorsened delusions, mania, suicidal ideation, eating disorder: People with mental illness who use AI chatbots risk experiencing a worsening of their condition, a new study shows. |
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News • Biofilm-based resistance mechanismBacteria build “bunkers” to withstand antibiotic treatment“The bacteria effectively hide in a bunker”: New research reveals a surprising mechanism used by Acinetobacter baumannii and Pseudomonas aeruginosa to protect themselves from antibiotics. |
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News • Flexible electronics implant“Cyborg” transplant could fix diabetes damage to the pancreasResearchers have created a ‘cyborg’ pancreas device - an ultrathin mesh of conductive wires within growing pancreatic tissue - that could open up new ways for treating diabetes. |
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| 41st Annual Congress of the European Association of Urology (EAU) | |
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