Search for: "diabetes" - 579 articles found

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Subgroup detected

A new Diabetes classification?

The traditional classification of diabetes, mainly in type 1 and type 2 diabetes, has been challenged by studies from Scandinavia. In the current issue of The Lancet Diabetes & Endocrinology, researchers from DDZ together with colleagues from DZD and University of Lund published a cluster analysis of diabetes allowing for phenotyping into subgroups, which extended the findings by showing that…

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Intervention in fat metabolism

Improved diabetes in spite of obesity

Eating too much fat and sugar makes you overweight and unhealthy – even young children know that. But why is that, and is there anything we can do about it? In a study published in the journal Cell, Prof. Jens Brüning's research group at the Max Planck Institute for Metabolism Research in Cologne has shown how altering fat metabolism in the liver can make obese mice thinner, despite eating an…

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Cost-effective telemedical eye screening

Smartphones save sight

About one in ten people in southern India is diabetic. Around one in three suffers from a so-called diabetic retinopathy (DR), a disease of the retina caused by diabetes. Untreated, DR is often the cause of visual impairment and blindness. However, many of those affected have symptoms only in the late stages of the disease. Early detection is therefore all the more important in order to intervene…

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Stop progression

Weight loss sets back Type 2 diabetes for at least two years

More than a third of people with Type 2 diabetes who took part in a weight management programme delivered by the NHS through GP surgeries remain free of diabetes two years later. These latest findings of the Diabetes Remission Clinical Trial (DiRECT), funded by Diabetes UK and led by experts at Newcastle University and the University of Glasgow, were announced today at Diabetes UK’s…

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Obesity and Type 1 diabetes

Robotic pancreas transplant offers hope

For patients with Type 1 diabetes who don’t respond well to insulin or have other serious medical complications caused by their disease, pancreas transplantation offers hope for a cure. But obese candidates who need a pancreas transplant often are denied the procedure because of poor outcomes, including high rates of incision infections, which are linked to an increased risk for failure and…

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Sysmex

With the UN-Series, the choice is yours

Using urine to obtain diagnostic insights has been done for thousands of years and still remains an important tool to obtain crucial information. Covering a range of tests, urinalysis may be used to screen for or help to diagnose ailments such as urinary tract infections, kidney disorders, liver problems, diabetes or other medical conditions, just to name a few. Because urinalysis has been around…

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Unhealthy lifestyle

How working night shifts raises your risk of type 2 diabetes

Women who work intermittent night shifts and do not follow a healthy lifestyle face an especially high risk of type 2 diabetes, suggests a study published by The BMJ. The researchers found that the risk of type 2 diabetes is actually higher than simply adding the individual risks associated with unhealthy lifestyle and shift work together, indicating that combining an unhealthy lifestyle with…

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Neuropathy

How to protect your feet from diabetes

Diabetes is a disease that can cause a host of accompanying problems, for example nerve dysfunction that can lead to diabetic feet. John Giurini, DPM, Chief of Podiatric Surgery at Beth Israel Deaconess Medical Center, talks about where these complications come from and what can be done to deal with them.

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Transthyretin amyloid cardiomyopathy

New treatments for rare disease ATTR-CM approved

The U.S. Food and Drug Administration (FDA) approved Vyndaqel (tafamidis meglumine) and Vyndamax (tafamidis) capsules for the treatment of the heart disease (cardiomyopathy) caused by transthyretin mediated amyloidosis (ATTR-CM) in adults. These are the first FDA-approved treatments for ATTR-CM. Vyndaqel and Vyndamax have the same active moiety, tafamidis, but they are not substitutable on a…

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Good boy, indeed

Diabetes: Dogs can help manage hypoglycaemic episodes

New research by the University of Bristol in collaboration with Medical Detection Dogs has found that the best trained alert dogs have the potential to vastly improve the quality of life of people living with Type 1 diabetes. As reported in PLOS One, on average trained dogs alerted their owners to 83 per cent of hypoglycaemic episodes in over 4,000 hypo- and hyper-glycaemic episodes that were…

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Aiming to drive health investments

Dubai’s notable healthcare

Formed in 2007 – under the directives of Sheikh Mohammed bin Rashid Al Maktoum, the Vice President, Prime Minister, and Ruler of Dubai, UAE – the Dubai Health Authority (DHA) oversees the healthcare system. Driven by the private sector, the country’s healthcare growth is a notable success story. We asked Dr Ibtesam Al Bastaki, Director, Investments & PPP’s at DHA about the vision for…

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Hope for diabetics

Insulin-producing cells grown in lab

UC San Francisco researchers have for the first time transformed human stem cells into mature insulin-producing cells, a major breakthrough in the effort to develop a cure for type 1 (T1) diabetes. Replacing these cells, which are lost in patients with T1 diabetes, has long been a dream of regenerative medicine, but until now scientists had not been able to figure out how to produce cells in a…

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More than a symptom

Chronic pain: a real disease after all?

For the first time ever, chronic pain will be classified as a diagnosis in line with other diseases when the World Health Organization (WHO) approves the next catalogue of recognised diseases in May. According to Professor Peter Svensson from the Department of Dentistry and Oral Health, this is very significant for the approx. 20% of the population who suffer from chronic pain. Working with top…

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Early detection

Prediabetes: don't wait, reduce your CVD risk

A diagnosis of prediabetes should be a warning for people to make lifestyle changes to prevent both full-blown diabetes and cardiovascular disease (CVD), according to scientists at Wake Forest School of Medicine. “We know that having diabetes increases the risk of developing cardiovascular disease, so in our study we wanted to determine what the absolute risk or probability of developing heart…

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Surprising similarities

These are the top 25 medical lab tests around the world

A recent study can help governments understand which diagnostic laboratory tests are most important when developing universal health coverage systems. Researchers from five countries found that diagnostic laboratory tests are used similarly around the world, even though the institutions they studied differed in terms of poverty levels, health systems and prevalence of disease. “Even though…

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Oncology

Killing the unkillable cancer cells

We all know someone affected by the battle against cancer. And we know that treatments can be quite efficient at shrinking the tumor but too often, they can’t kill all the cells, and so it may come back. With some aggressive types of cancer, the problem is so great that there is very little that can be done for the patients.

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Cause and effect

Diabetes and heart failure: discovering the connection

Men with diabetes are 2.4 times more likely than non-diabetics to suffer heart failure and women are five times more likely. But why? A new Loyola University Chicago Stritch School of Medicine study reveals how, on a cellular level, diabetes can cause heart failure. The findings could lead to medications to treat and perhaps prevent heart failure in diabetes patients, researchers said. In a…

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High blood pressure

Hypertension: treatment disadvantage in the south

Healthcare in low- and middle-income countries is poorly prepared for the increasing number of people with high blood pressure, with more than two-thirds of people affected going without treatment – a new study reveals. Researchers studied health data for one million people in the Global South, discovering that less than half of those affected are diagnosed with high blood pressure or…

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MERS-CoV

Seeking answers to combat Middle East respiratory syndrome

With a case fatality rate of 35 percent, a Middle East respiratory syndrome-related coronavirus (MERS-CoV) infection – also called camel flu – is a dangerous disease. About seven years ago, when the virus was first isolated, mortality was close to 100 percent since only severe infections that led to the patient being in intensive care were recorded. Today the environment of each victim is…

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Dysbiosis treatment

New prebiotics: benefits without downsides?

Prebiotics are currently a preferred treatment for certain metabolic disorders, as they can restore the balance of dysfunctional gut microbiota, and improve the body’s metabolism. However, these substances have to be used at high doses, which can result in patients experiencing bloating and flatulence. A research group led by Matteo Serino, Inserm researcher at the Digestive Health Research…

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LITMUS vs NAFLD

Towards better diagnosis and treatment of liver disease

A pioneering European research project designed to develop new diagnostic tests to assess patients with Non-Alcoholic Fatty Liver Disease (NAFLD) has expanded giving access to more patients. Liver Investigation: Testing Marker Utility in Steatohepatitis (LITMUS) funded by the European Innovative Medicines Initiative 2 Joint undertaking, brings together clinical scientists from international…

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Healthy heart

How the 'blue' in blueberries can lower blood pressure

A new study published in the Journal of Gerontology Series A has found that eating blueberries can lead to an improvement in blood vessel function and a decrease in systolic blood pressure. Researchers from King’s College London and the University of Surrey studied 40 healthy volunteers for one month. They were randomly given either a drink containing 200g of blueberries, or a matched control…

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Meeting of the generations

We need a Senior Laboratory

It’s undeniable: the bulk of our population is growing older. Yet, this demographic change has not altered laboratory medicine: the reference values for many analyses are still based on data of a younger cohort. Inevitably this could lead to serious errors in the interpretation of older patients’ test results. Professor Kai Gutensohn, Managing Director and Medical Director of AescuLabor…

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POC analysis

A revolution in HbA1c measurement

Quo-Lab® HbA1c is a desktop point-of-care analyzer for measuring glycated hemoglobin (HbA1c). The semi-automated analyzer has been designed specifically to meet the needs of diabetes clinics and laboratories in settings that demand low cost of operation and ease of use. From a simple procedure, Quo-Lab provides lab-accurate test results within four minutes (CV < 3% at 7% A1c) from a venous or…

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Thrombocytes

Blocking platelets could prevent fatty liver disease and liver cancer

Non-alcoholic fatty liver disease is among the most common chronic hepatic disorders in Western industrial countries and the rate is also rapidly rising in newly industrialized countries. Experts estimate that about 30 to 40 percent of the population worldwide develop this liver condition. In the United States, this disease is well on the way to becoming the most frequent indication for liver…

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Old as mice

When less is more: Gene switch for healthy aging found

Aging is a major risk factor for physical frailty and the development of age-related diseases such as cancer, cardiovascular diseases, type II diabetes and Alzheimer's disease. Numerous studies have already shown that a calorie-restricted diet can significantly delay age-related conditions in several organisms like flies, worms, fish and mice, and that it even improves fitness at old age. But who…

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Cancer research

Black nanoparticles slow tumor growth

Melanin protects our skin from the sun’s damaging rays by absorbing light energy and converting it to heat. This could make it a very effective tool in tumor diagnosis and treatment, as demonstrated by a team from the Technical University of Munich (TUM) and Helmholtz Zentrum München. The scientists managed to create melanin-loaded cell membrane derived nanoparticles, which improved tumor…

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T-2-weighted imaging

When the brain turns white

White matter on the brain is a difficult subject. Even the terminology is varied, making differential diagnosis complex. An understanding of prevalence and of the tools available to facilitate the diagnosis of individual diseases is important, Dr Gunther Fesl, radiologist at Praxis Radiologie Augsburg, explains. ‘Differential diagnosis of white matter on the brain is difficult. Even the…

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Glucose control

"Sugar sponges" - diabetes treatment of the future?

Many diabetes patients must inject themselves with insulin, sometimes several times a day, while others take medications orally to control blood sugar. The injections, as well as the side effects from both regimens, can be painful. Now, one team reports in the Journal of the American Chemical Society progress toward an insulin-free diabetes treatment that requires fewer injections.

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Paradigm shift

Diabetes has 5 subtypes, not 2, study suggests

A completely new classification of diabetes which also predicts the risk of serious complications and provides treatment suggestions. We are now seeing the first results of ANDIS – a study covering all newly diagnosed diabetics in southern Sweden — published in The Lancet Diabetes & Endocrinology. The major difference from today’s classification is that type 2 diabetes actually consists…

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The AßC of diabetes

Smart artificial beta cells could lead to new diabetes treatment

Treating type 1 diabetes and some cases of type 2 diabetes has long required painful and frequent insulin injections or a mechanical insulin pump for insulin infusion. But researchers from the University of North Carolina and NC State have now developed what could be a much more patient-friendly option: artificial cells that automatically release insulin into the bloodstream when glucose levels…

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Not so sweet after all

Could sugar be responsible for the obesity and diabetes epidemics?

The idea that sugar could be a fundamental cause of the global obesity and diabetes epidemics, with deleterious effects on the human body that go beyond just empty calories, should be considered seriously again, argues journalist and author Gary Taubes in The BMJ. In the midst of such a huge public health crisis, Taubes says “we must do more to discourage consumption while we improve our…

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Epidemiological study

Vitamin D deficiency linked to increased diabetes risk

An epidemiological study conducted by researchers at University of California San Diego School of Medicine and Seoul National University suggests that persons deficient in vitamin D may be at much greater risk of developing diabetes. The scientists studied a cohort of 903 healthy adults (mean age: 74) with no indications of either pre-diabetes or diabetes during clinic visits from 1997 to 1999,…

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Smoking cessation

Common diabetes drug may also help with nicotine withdrawal

In a mouse study, a drug that has helped millions of people around the world manage their diabetes might also help people ready to kick their nicotine habits. In a report published in The Proceedings of the National Academy of Sciences of the United States of America (PNAS), investigators say metformin, an inexpensive drug commonly used to treat patients with type 2 diabetes, appears to block…

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Better together

Making diabetes and hypertension management a community activity

Managing diabetes and high blood pressure can feel like a solitary enterprise dependent on relationships with objects (like pills or foods) and activities (like brisk walks or early bedtimes) instead of relationships with people, but a group of West Virginia University researchers is hoping to change that. The National Institutes of Health has awarded $450,000 to Ranjita Misra, a professor of…

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Additive manufacturing

3D printing: customized insoles for diabetes patients

In the past, insoles for patients with diabetes were hand-made by orthopedic shoemakers. In the future, these specialist shoemakers will be able to produce insoles more cost-effectively thanks to new software and the use of 3D printers. This approach means the mechanical properties of each insole can be assessed scientifically and more effectively.

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Efferocytosis

Can stem cell exosome therapy reduce fatal heart disease in diabetes?

Macrophage cells routinely remove dead or dying cells to maintain the body homeostasis. Such removal becomes crucial after serious injury, especially the repair of dead heart muscle after a heart attack. University of Alabama at Birmingham researchers have preliminary data, with cultured cells or diabetic hearts, that diabetes impairs this removal of dead heart-muscle cells. They believe this…

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Risk of complications

Diabetes prolongs hospital stays

One in four patients in a university hospital suffers from diabetes (22 percent), and again as many suffer from prediabetes (24 percent), a current study finds. Furthermore, patients with diabetes have prolonged hospital stays and a higher risk of complications.

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Diabetes

Recommended blood pressure targets are being challenged

The Swedish National Board of Health and Welfare recently raised the recommended target blood pressure for patients with diabetes. This may lead to more patients suffering from stroke or heart attack, according to a new study from the Sahlgrenska Academy. The new study is the world’s largest on the subject and is based on data from the National Diabetes Register.

Qualification

Diabetes-Nanny

About 25,000 German children are diabetic, and numbers are increasing rapidly. Specialists in childhood diabetes gathered at a meeting held by the Dianino Foundation during the 41st Annual Meeting of German Diabetes Society (DDG), to discuss `Diabetes-Nanni´, a programme in which female diabetes advisers receive additional psychology training to care for diabetes-affected families in their homes.…

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Birth outcome study

Obesity and pregnancy: A risky couple

New research from the University of Adelaide’s Robinson Research Institute supports the need for dietary and lifestyle interventions before overweight and obese women become pregnant. The researchers have reported the results of a large study of birth outcomes in more than 500 overweight or obese women from three public maternity units in Adelaide, Australia in The Lancet Diabetes &…

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Diabetes

Friendly Fire in the Pancreas

n type 1 diabetes, the body attacks its own insulin-producing cells. Scientists at Helmholtz Zentrum München, partner in the German Center for Diabetes Research, and their colleagues at Technical University of Munich have now reported in the journal ‘PNAS’ about a mechanism used by the immune system to prepare for this attack. They were able to inhibit this process through targeted…

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Diabetes management

This April, scientists, physicians, nurses, diabetes organisation heads, patients and representatives from Bayer HealthCare Diabetes Care gathered in Basel, Switzerland, for the third European Media Workshop on Diabetes. The event was hosted by Bayer HealthCare Diabetes Care, which is celebrating 40 years of innovative blood glucose monitoring.

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Hepatology

Fatty liver: especially dangerous during the holidays

More than 100 million Americans have potentially deadly fatty liver disease and most do not even know it. Overeating and drinking excessive amounts of alcohol this holiday season could put someone with the disease on the fast track to liver failure. “There are no symptoms associated with fatty liver disease and no pain, so most people never get checked or treated for it and, over time, if it is…

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Integration to combat diabetes

To face the national and worldwide increase in diabetes mellitus cases, the German Federal Ministry of Education and Research initiated the foundation of the German Centre for Diabetes Research (DZD), aiming to improve basic research, prevention, diagnostic and therapy of diabetes. Inaugurated in Berlin a few months ago, the centre has five strategic partners.

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Europe's diabetes dilemma

The difference in the prevalence of diabetes in European countries is striking. Meike Lerner asked Sir Michael Hirst, Vice President of the International Diabetes Federation, why, for example, Germany has the highest number of diabetics (about 12% of the population) whilst the United Kingdom shows just 4%.

Growing up with diabetes

Diabetes presents a special challenge for the young. Here we see how a young Swiss girl has successfully come to terms with her metabolic disorder. A true life story from Bayer HealthCare Diabetes Care (BayNews)

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New marker for diabetes

This week not only one but rather two studies report about a new and independent marker that is associated with type 2 diabetes. The protein that is called fetuin-A is produced in the liver and secreted to the blood stream also indicates a higher risk of developing diabetes disease.

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Regulatory B cells

Researchers identify new marker for autoimmune disorders

The immune system is a complex and precisely regulated system. Various activating and inhibiting signals ensure that the immune cells combat pathogenic agents without eliciting a potentially harmful response to its own structures and cells. However, if those two forces are imbalanced, the immune cells may attack and damage cells and tissue of the body itself, which will result in the development…

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Diabetes research

Novel transcriptomic signature of type 2 diabetic islets identified

Type 2 diabetes, which affects >0.5 billion people worldwide, results from the inability of beta cells in the pancreatic islets to provide the body with enough insulin to maintain blood glucose levels within the range for a healthy life. A collaborative study led by Prof. Michele Solimena at the Technische Universität in Dresden as well as the Helmholtz Zentrum München, Dr. Anke M Schulte at…

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Research

Unravelling the mystery of non-alcoholic fatty liver disease

Another piece in the puzzle that is non-alcoholic fatty liver disease has been solved by a University of Queensland researcher in a step towards developing treatments for a disease that affects about one in every five Australians. PhD student Laurence Britton has discovered a pivotal mechanism by which iron is able to make the liver more vulnerable to the injury and metabolic dysfunction that…

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Emergency rise for child diabetes

Since 2002 the number of children in England needing hospital care for complications of diabetes has risen about approximately 25 percent. The Patient group Diabetes UK blames cuts in the NHS service for this trend, BBC News reported yesterday.

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Better diabetes care for the UK

Good news for diabetes patients in the UK: According to a report published recently by the Department of Health, diabetes care in the NHS is improving and focusing more on prevention. The result: More patients have been identified, and in more people at risk development of the condition could be prevented.

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Study

Risk factors on rise among people with stroke

Despite prevention efforts, researchers have found a significant increase over a 10-year period in the percentage of people with stroke who have high blood pressure, diabetes, smoking and other risk factors for stroke. “An estimated 80 percent of all first strokes are due to risk factors that can be changed, such as high blood pressure, and many efforts have been made to prevent, screen for and…

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Global perspectives on diabetes

Despite Hurricane Amma storming over Prague, hundreds of medical specialists paid little attention when they attended the 1st International Conference on Advanced Technologists and Treatments for Diabetes (ATTD), observed our Russian correspondent Olga Ostrovskaya, reporting on the International Conference on Advanced Technologies & Treatments for Diabetes (ATTD) in Prague (ATTD) held in…

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Type 2 diabetes driving epidemic

Type 2 diabetes poses one of the greatest public health threats of the 21st century. The majority of the western world is in the grips of a diabetes epidemic driven by type 2 diabetes that goes hand in hand with the escalating incidence of obesity. Alarmingly, in some working class and poor communities, the disease is so prevalent that its victims almost take it as a matter of course.

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I see diabetes in your eyes

Diabetes fires researchers imagination: Two scientists at the University of Michigan Kellogg Eye Center developed a new screening device that gives early warnings of diabetes and its vision complications within five minutes.

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Gastrin analogue against diabetes

Transition Therapeutics Inc. announced that the first patient has been dosed in a Phase 2 clinical study of gastrin analogue, TT-223, in patients with type 2 diabetes. Gastrin based therapies are an emerging class of potential disease-modifying treatments for patients with diabetes.

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Handheld devices

The pocket-size lactate monitor

Made by EKF Diagnostics, the Lactate Scout 4 hand-held analyser is a fast, accurate sports performance monitoring device designed for use as a training companion for individuals or sports teams. This year at Medica the manufacturer is showing the new analyser plus many POC testing devices, including the recently FDA cleared DiaSpect Tm haemoglobin analyser and Quo-Lab® HbA1c analyser that was…

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Artificial beta cells

New weapon against Diabetes

ETH Researchers have used the simplest approach yet to produce artificial beta cells from human kidney cells. Like their natural model, the artificial cells act as both sugar sensors and insulin producers.

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Nantes CHU

A hospital designed to fit 21st century medicine

21st century challenges are multitudinous for all. Ageing populations, a changing disease burden; increasing obesity with associated morbidities – Type 2 diabetes, cancer and cardiovascular disease; climate change pressures and more. Any new build plan demands a low carbon footprint; respect for the environment is paramount. To capture all those elements, the plan to regenerate a previously 10…

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Prevention

Next step in preventing diabetes

A team of scientists at Helmholtz Zentrum München, in collaboration with Technische Universität München and the German Center for Diabetes Research (DZD), have shown in a preclinical model that specifically modified insulin mimetopes may lead to an immune tolerance. The results, published in ‘Nature Communications’, may be a step to improved prevention of type 1 diabetes.

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SWEET news: A paediatric diabetes network

For three years the SWEET project, funded by the EU and the International Society for Paediatric and Adolescent Diabetes (ISPAD), has been preparing the establishment of centres of reference (CORs) for childhood diabetes. Now, the first 12 European CORs that are certified by SWEET have joined forces to promote improved cross-border cooperation in the treatment of young Type 1 and Type 2 diabetics.

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Diabetes and CAD

Anja Behringer reports on a neglected risk factor. With an aging population multimorbidity is increasingly a major challenge for hospital care. Diabetes is one of the medical conditions frequently encountered in multimorbid patients since cardiac and vascular diseases are often accompanied by dysfunctions of the blood sugar metabolism.

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Chronic obstructive pulmonary disease

COPD: Biomarker for kidney disease has unexpected benefits

A commonly used biomarker of kidney disease may also indicate lung problems, particularly COPD, or chronic obstructive pulmonary disease, according to new research published online in the American Thoracic Society’s American Journal of Respiratory and Critical Care Medicine. In “Albuminuria, Lung Function Decline, and Risk of Incident COPD: the NHLBI Pooled Cohorts Study,” Elizabeth C.…

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Biology of Ageing

Road map to a longer life

In old age a variety of cellular processes decline and the risk to develop age-related diseases such as Alzheimer’s, Parkinson’s or Diabetes increases dramatically. But does ageing affect all organs and tissues in the body in the same way? And should drugs that are developed to improve health in old age have the same effect on every organ? Now scientists from the Max Planck Institute for…

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Diabetes: an increasing threat to people and society

Approximately 31 million people in the European Union are suffering from diabetes, a devastating disease with severe consequences for patients and their families, but also for the society at large and the economic prosperity of Europe. This week EH Online will focus on innovative strategies in diabetes care and on new management systems to support physicians and patients alike. Moreover, we will…

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Embracing the digital age

France simplifies healthcare

Successful pilot scheme means TERR-eSanté will be rolled out for the whole of the Ile-de-France. The French have a reputation as early adopters of telemedicine driven by the desire to modernise healthcare by the judicious use of the latest technology. The first ‘carte vitale’ (national health card) with a microchip was introduced in 1998. Since 2011, the information stored on the cards has…

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Cardiology congress

ESC 2018: At the heart of research

When delegates from around 150 countries converge on Munich for ESC Congress 2018 they will no doubt reflect on what they themselves eat. Yes, nutrition is up for debate, questioning, for example, whether weight loss therapies can also prevent heart attacks and strokes. Results from the CAMELLIA-TIMI 61 trial of 12,000 overweight individuals with established cardiovascular disease or diabetes…

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Research

Link between diabetes and bone health

Diabetes, which now affects almost 30 million Americans, can cause serious health complications, including heart disease, blindness, kidney failure and lower-extremity amputations. A lesser-known but equally grave complication is the effect of diabetes on bone health.“Clinical trials have revealed a startling elevation in fracture risk in diabetic patients,” says Liyun Wang, associate…

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AACC News

New tests to diagnose and monitor diabetes

Researchers have successfully tested two new potential methods for diagnosing and monitoring diabetes in its standard and gestational forms. These findings, presented at the 2015 AACC Annual Meeting & Clinical Lab Expo in Atlanta, may lead to easier, timelier, and more affordable ways of identifying and treating this chronic disease.

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Imaging for diabetes and vascular occlusive disease

Metabolic syndrome, diabetes and vascular disease: What do we need to know? During ECR session this important question is addressed by vascular specialist Professor Erich Minar, Assistant Head of the Department of Angiology at the Vienna General Hospital (AKH), President of the Austrian Society of Angiology, and scientific researcher working closely with research centres in the USA.

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Gastric bypass undoes diabetes symptoms

French findings support the notion that gastric bypass can rapidly reverse diabetes symptoms' a side-effect that lap-band surgery does not show. The benefit results from a new-found element of glucose production by the intestine which also increases insulin sensitivity and lowers blood sugar.

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Diabetes management in the hospital

Diabetes mellitus is a lingering disease – for a long time it causes subjectively few complaints or no complaints at all. Despite this, it is life-threatening – especially if undiagnosed, or diagnosed too late. However, although diabetes is the most widespread disease it is often only discovered by accident in a hospital, where many hospital doctors feel that diabetology is the responsibility…

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Broken immune clock

Why shift work might be to blame for obesity and diabetes

About 15 million Americans don’t have a typical nine-to-five workday, and many of these—nurses, firefighters and flight attendants, among many other professions—may see their schedule change drastically one week to the next. As a result, these shift workers’ biological clocks, which keep track of the time of day, cannot keep accurate time, potentially making the negative effects of a high…

World Diabetes Day

Born in 1891, Canadian Sir Frederick Banting was destined to become a medical scientist and Nobel Prize winner for work that led to the discovery of insulin. World Diabetes Day, held on his birthday, aims to sensitise the public - including potential patients - to this condition. Worldwide, around 245 million people suffer Diabetes mellitus. With 5.3 million of them in Germany, the country's…

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Risks and benefits of first line diabetes treatment

Although the drug metformin is considered the gold standard in the management of type 2 diabetes, a study by a group of French researchers published in this week's PLoS Medicine suggests that the long-term benefits of this drug compared with the risks are not clearly established - an important finding given that currently, thousands of people around the world are regularly taking metformin to…

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Typ 2 Diabetes: Is low cholesterol associated with cancer?

Yes, it is, according to a prospective cohort study published in CMAJ. The study was conducted by researchers from the Hong Kong Institute of Diabetes and Obesity, the Li Ka Shing Institute of Health Science and The Chinese University of Hong Kong. Their result: A V-shaped risk relation between LDL cholesterol and cancer in patients not receiving statin therapy.

The Norfolk Diabetes Prevention Study

UK -- Family doctors (GPs) in Norfolk are inviting patients aged over 40, with a Body Mass Index above 30 and a family history of diabetes, to take part in the Norfolk Diabetes Prevention Study (NDPS). Funded by the National Institute for Health Research, the innovative £2.2million project will run for five years at the Norfolk and Norwich University Hospital (NNUH) and will involve 10,000…

31st Annual Cardiologists Conference

Every heart beat counts

The term “Cardiology” means the division of science that converses functions, diseases and health activities related to heart. It is also connected with blood, arteries and veins, as blood is the vital component of human body, upon which the heart works and for it we survive. The world cardiology market includes cardiac biomarkers, interventional cardiology and cardiovascular devices. The…

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Infection control

Local antibiotics improve results

Hip and knee joint surgeries are among the most common procedures in orthopaedics and trauma surgery and complications can occur. Rare, but serious, among these is periprosthetic joint infection (PJI), which causes high costs in healthcare and stress for patients. PJI is caused by microorganisms that form a biofilm on the surface of the implant and, in this sessile state, they are difficult to…

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AACC Disruptive Technology Award

Developers take diagnostics to the patient

Over the last several years, technological advancements have enabled the development of tests that can be performed right where the patient is, whether that’s in a hospital room, primary care office, or community health center. This is a paradigm shift in healthcare delivery that will make it easier for patients to get accurate diagnoses and treatment, and could especially benefit patients in…

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Want to take part in clinical trials?

People with diabetes are often interested to be involved in research trials, according to the patient organization UK Diabetes. Therefore, the Diabetes Research Network (DRN) announced an initiative which shall help diabetics to play a greater role in research.

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Cholesterol-lowering medication

Statins overprescribed for primary prevention

Taking cholesterol-lowering drugs, or statins, as a preventive measure can reduce the risk of cardiovascular disease. A study by the University of Zurich now shows that this measure is recommended too often, as current guidelines fail to take into account the risks of side effects. Even healthy people who don't suffer from a cardiovascular disease are prescribed statins if they meet certain risk…

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Cardio app

AI system screens early Phase AFib

Here at Medica, the Taiwanese start-up Maisense is demonstrating Freescan, its artificial intelligence (AI) based solution to screen for stroke through the early detection of atrial fibrillation (AFib). Speaking of the system’s aims, Maisense summed up this huge health problem. ‘Every four minutes, someone dies of stroke. Thirteen percent of these are classified as haemorrhagic stroke. When…

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Glucose metabolism

Sugar and stress: how are they connected?

Chronic stress is a well-known risk factor for the development of psychiatric illnesses including depression disorders. The brain requires a great deal of glucose, and stress is known to alter glucose metabolism. However, if stress-associated mental impairments are linked to affected glucose metabolism remains to be seen. Researchers at the Department for Psychiatry and Psychotherapy at the Mainz…

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Not such a bad egg after all

Daily egg consumption may reduce cardiovascular disease

People who consume an egg a day could significantly reduce their risk of cardiovascular diseases compared with eating no eggs, suggests a study carried out in China, published in the journal Heart. Cardiovascular disease (CVD) is the leading cause of death and disability worldwide, including China, mostly due to ischaemic heart disease and stroke (including both haemorrhagic and ischaemic…

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Education for the best disease management

At the opening of the Johnson & Johnson Diabetes Institute in Paris experts took the opportunity to warn against the growing incidence of diabetes. They reinforced the believe that improved education measures as a key enabler for patients to better manage the condition. They predicted that in 2025 the number of people with diabetes wil have increased by 20 percent in Europe.

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Seeking the genetic basis of diabetes

Researchers have identified 12 new genes associated with Type 2 diabetes (T2D) that look set to improve the understanding of the processes underpinning the condition. The findings could also offer new biological pathways that can be explored as targets for new therapies to tackle T2D.

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Single nucleotide polymorphism

Biosensor chip detects genetic mutation with higher sensitivity

A team led by the University of California San Diego has developed a chip that can detect a type of genetic mutation known as a single nucleotide polymorphism (SNP) and send the results in real time to a smartphone, computer, or other electronic device. The chip is at least 1,000 times more sensitive at detecting an SNP than current technology. The advance could lead to cheaper, faster and…

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Diabetes I

Diabetology news

The focus of the 2015 Diabetes Congress held in Berlin this May was ‘Personalised diabetes treatment: innovative – individual – sustained’. EH reports on points aired during the supporting press briefing. Report: Bettina Döbereiner

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Diabetes doubles CVD risk

A team led by UK-based researchers has found that having diabetes doubles the risk of developing a wide range of blood vessel diseases, including heart attacks and different types of stroke. The consortium, headed by Dr Nadeem Sarwar and Professor John Danesh of the University of Cambridge, analysed data from the individual records on 700,000 people, each of whom was monitored for about a decade…

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Hopes for new treatment

Researchers have discovered a potential new treatment for diabetes by isolating and killing defective cells which prevent the natural production of insulin. The investigation opens the door to a potential therapy for patients with type 1 diabetes.

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Long-term communication success in digitised healthcare

E-health in Denmark

The Danes have shown for some time how e-health can work successfully on a national level. The health portal sundhed.dk (= health), initiated in 2001 and launched in 2003, is part of the public healthcare system. As of January 2018, the Danish national strategy describes sundhed.dk as a national access point for personal health-related data for hospitals, general practitioners and communities,…

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Dementia

Drinking will put your brain at risk (but then again, abstinence might, too)

People who abstain from alcohol or consume more than 14 units a week during middle age (midlife) are at increased risk of developing dementia, finds a study in The BMJ today. However, the underlying mechanisms are likely to be different in the two groups. As people live longer, the number living with dementia is expected to triple by 2050. So understanding the impact of alcohol consumption on…

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Postprandial blood glucose

The daily management of diabetes mellitus is a complex interaction between blood glucose measuring, lifestyle aspects and drug therapy. Large epidemiological trials such as UKPDS (United Kingdom Diabetes Prospective Study) have shown that an optimal blood glucose adjustment has beneficial long-term effects on type-2 diabetics’ risk of micro- and macrovascular secondary complications.

Insulin regulates itself

In type 2 diabetes, which is occurring at alarming rates, the hormone insulin does not work effectively to lower blood sugars and patients also do not make enough insulin. These two processes have been widely considered as separate. However, a surprising discovery was made by Joslin Diabetes Center researchers in animal models of diabetes: insulin is important in regulating its own production.…

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Endoprosthetics

Joint efforts: New guidelines for arthroplasty

According to the Swedish Knee Arthroplasty Register, knee arthroplasty – with a revision rate of five percent after ten years – is one of the most successful surgical interventions of the post-World War II decades. The most frequent reasons for revision are loosening or infections, whereas patient dissatisfaction is often caused by mobility impairment and pain. Since many adverse events are…

Endocrine Society: No change in blood sugar control goals

A study published this week in Lancet suggests that low A1C levels may be just as dangerous as high A1C levels in diabetes patients with respect to mortality and cardiovascular outcomes. Upon review of the study, The Endocrine Society released a statement recommending against any wholesale change in glycemic goals and strongly encourages patients to discuss these issues with their diabetes-care…

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Wound care

Healing helped by fish skin or bio-ink

Many methods to treat current or chronic wounds are available. However, the differences in general conditions prevailing in hospital, or for out-patient care, make effective therapy more difficult. Each patient also has other preconditions for healing. Improved communication between everyone involved in the treatment would benefit patients. We see a lot of progress with the issue of “wounds”,…

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‘It will be worthy and cost effective’

Belgium sets up a DX pathology platform

As in many other countries, Belgium faces a significant shortage of health professionals – particularly pathologists to guarantee the diagnostic quality necessary for adequate therapeutic choice. A digital pathology platform can be a true ally; the Brussels Erasmus Hospital opted for that solution. Project manager Dr Ali Ramadhan shared his experience – the good, the bad and the ugly – at…

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Diabetics must lower their risk of CVD

Diabetics can face a five times increase in the risk of developing cardiovascular disease (CVD) than non-diabetics. This leads to a seven to ten year reduction in life expectancy and a higher probability of suffering a fatal heart attack. These sad statistics have prompted the European Society of Cardiology (ESC) to mark World Diabetes Day on 14 November by emphasising the simple measures that…

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Cerebrovascular disease

Stroke deaths decrease all over Europe – but it's too early to cheer

New research, published in the European Heart Journal, has shown deaths from conditions that affect the blood supply to the brain, such as stroke, are declining overall in Europe but that in some countries the decline is levelling off or death rates are even increasing. Cerebrovascular disease includes strokes, mini-strokes, and narrowing, blockage or rupturing of the blood vessels supplying…

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Stop transplanted insulin cells from dying

Researchers at Linköping University and Uppsala University in Sweden can show that accumulation of protein aggregatess, amyloid, in the transplanted cells may be causing their death. With the aid of their results, physicians can enhance survival of islets transplants and improve treatment of type 1 diabetes.

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Bayer's new Contour meter and Microlet 2 devices

The new Contour blood glucose meter from Bayer HealthCare Diabetes Care promises enhanced testing features that can be personalised to meet diabetics individual treatments. The firm has also redesigned the Microlet 2 lancing system.

Trust leads research knowledge transfer

UHB is leading the way in creating key networks with other European centres of excellence to share knowledge between renowned specialists. The project is already enhancing the Trust’s profile as a focus of translational research in Service Delivery, Haematology, Liver Disease, Diabetes and e-Prescribing.

Artificial pancreas

Two small randomised trials published on bmj.com suggest that closed loop insulin delivery (also referred to as an artificial pancreas) may improve overnight blood glucose control and reduce the risk of nocturnal hypoglycaemia in adults with type 1 diabetes.

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Enjoying childhood - despite being a type 1 diabetic

Type 1 diabetes is a life-long autoimmune disease with onset in early childhood. The diagnosis will initially turn the everyday life of children and their families topsy-turvy due to blood glucose testing, insulin injections, thorough calculation of meals, etc. It takes time before all these new and often frightening procedures become part of the daily routine of small diabetics.

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Type 2 diabetics have elevated risk of 24 types of cancer

Type 2 diabetics run an elevated risk of developing cancer, according to the world’s largest study on the combined risk of diabetes and cancer, conducted by scientists at the German Cancer Research Centre (DKFZ). The study focused on 24 types of cancer. The effect is most evident for liver cancer and pancreatic cancer. However, by contrast, diabetics have a significantly lower rate of prostate…

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The pancreas as we’ve never seen it before

Professor Ulf Ahlgren and associates at Umeå University in Sweden are a leading research team in the world in the development of optical projection tomography. With the aid of this imaging technology, they have now described aspects of how the pancreas develops during embryonic development and how the so-called islets of Langerhans are distributed in the adult organ. The findings are important…

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The psychology of healing

People suffering from diabetes-related foot ulcers show different rates of healing according to the way they cope and their psychological state of mind, according to new research by a health psychologist at The University of Nottingham, UK. The large study published in the journal Diabetologia has shown that the way patients cope with the condition and their levels of depression, affect how the…

AACC publishes program for 2011 annual meeting

2011 The American Association for Clinical Chemistry (AACC) has published the program for its 2011 Annual Meeting being held July 23 – 28 at the Georgia World Congress Center in Atlanta, GA. This year the Annual Meeting features almost 300 individual educational events in a variety of formats. Hot topics for 2011 include cancer, obesity, diabetes, and healthcare reform.

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Carotid Stenting

Arteriosclerosis is well known as a vascular disease and cardiovascular risk factor. In its generalised form it affects not only the peripheral vessels (pelvis, legs) but also the coronary vessels and the carotid arteries. Arteriosclerosis is primarily a manifestation of advancing age, hence it is often accompanied by other diseases of the lungs and the heart as well as by metabolic diseases…

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Insulin-Produktion dank transplantierter Zellen

Die erste am Universitätsklinikum Carl Gustav Carus vorgenommene Transplantation von Inselzellen aus einer Bauchspeicheldrüse verlief erfolgreich: Zwei Wochen nach dem Eingriff bildet die seit 51 Jahren an Diabetes Typ 1 erkrankte Patientin wieder körpereigenes Insulin. Die Transplantation ist Ergebnis einer über zwei Jahre dauernden, aufwendigen Aufbauarbeit an Uniklinikum und Medizinischer…

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Glucose monitoring

Professor Oliver Schnell, of the Diabetes Research Institute, Munich, reports on discussions and findings of a panel of diabetes experts who met this summer in Switzerland

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Diabetes

No more Insulin injections?

In patients suffering from Type 1 diabetes, the immune system attacks the pancreas, eventually leaving patients without the ability to naturally control blood sugar. These patients must carefully monitor the amount of sugar in their blood, measuring it several times a day and then injecting themselves with insulin to keep their blood sugar levels within a healthy range. However, precise control…

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246 Million Euros for faster medicine development

Fifteen new research projects aimed at bringing innovative medicines to market faster have been selected to receive 246 million Euros from the European Commission and the European Federation of Pharmaceutical Industries and Associations (EFPIA). The projects will foster understanding of health issues such as diabetes, pain, severe asthma and psychiatric disorders while increasing medicine safety.

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Surgery proves successful for Type 2 diabetes remission

Obesity is physically debilitating – and costly for healthcare. Losing excess weight has positive effects on the entire metabolism and improves life expectancy. However, for patients who cannot lose their morbid, excess weight through diet, today’s surgical interventions can help towards permanent weight loss – and reduction in insulin dependency for diabetics.

Deadly disease, dismal summary

Recently, the prevalence of diabetes mellitus in the Czech Republic reached 7-8% (783,321 diabetics were treated last year – 419,362 females and 363,959 males) but this figure leaps to 25-30% for diabetes related hospitalisations.

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1000 Genomes Project publishes analysis of completed pilot phase

Small genetic differences between individuals help explain why some people have a higher risk than others for developing illnesses such as diabetes or cancer. In the journal Nature, the 1000 Genomes Project, an international public-private consortium, published the most comprehensive map of these genetic differences, called variations, estimated to contain approximately 95 percent of the genetic…

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The ESC Congress

25,000 visitors and medical professionals from 47 National Cardiac Societies across central and greater Europe, will attend the 2004 ESC Congress, where 'Diabetes and heart disease' will be the main theme. Lars Ryden, ESC Past-President, team member for the Euro-Heart Survey on Diabetes, and Chairman of the 'Guidelines for Diabetes & the Heart', and William Wijns, co-chair and Chairman of the…

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Genes

Blame your health problems on your grandfather

If you have diabetes, or cancer or even heart problems, maybe you should blame it on your dad’s behaviour or environment. Or even your grandfather’s. That’s because, in recent years, scientists have shown that, before his offspring are even conceived, a father’s life experiences involving food, drugs, exposure to toxic products and even stress can affect the development and health not…

Scales to fit all patients and needs

The Hamburg-based company seca has specialized in the manufacture of weighing and height measuring scales for over 165 years. Today, the firm has locations in Switzerland, the UK, France, Japan, China, Mexico and the USA, and manufactures products in Germany, the Czech Republic and China, and exports its range of products - which include infant, column and flat scales, with height measuring…

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Achieving HbA1c target values

An adequate blood glucose level (4–7 mmol/l) is important not only for a diabetic’s daily well-being but also to prevent diabetes-related illnesses. HbA1c is the central marker to evaluate the success of diabetes management. But HbA1c measurement has a crucial limitation: current blood glucose fluctuations are not taken into consideration. However, the recognition of steep post-prandial blood…

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46th EASD Annual Meeting

Professor Claes-Göran Östenson, chair of the Local Organising Committee of the 46th European Association for the Study of Diabetes annual meeting, will welcome visitors in this the bicentenary year of the renowned Nobel-prize giving Karolinska Institute. Since its foundation in 1965, the EASD annual meeting has become the world’s largest international annual conference on diabetes research,…

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Self-monitoring of blood glucose

Around 75% of adult type 1 and type 2 diabetics say they believe they know what their blood sugar levels are, without testing, according to data presented at the American Diabetes Association 70th Scientific Sessions. These results are important to consider because self-monitoring with a blood glucose meter is essential for people with diabetes to obtain accurate blood glucose results that guide…

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When and how should we start insulin?

Innumerable studies (e.g. Ceriello A., et. al. 2006) have shown that postprandial hyperglycaemia is an independent risk factor for cardiovascular disease (CVD) in all populations. In diabetics, according to IDF figures, CVD is even the major cause of death (some 50 % of all diabetes fatalities) and much disability. ‘Therefore, the primary goal in diabetes treatment should be not only lowering…

Glucose monitoring: from lab to POC?

According to estimates up to 450 million patients will suffer from diabetes in the year 2025 (currently 250 million). In view of this, glucose monitoring is of utmost importance. Scientific studies and practical experiences with glucose monitoring at the point of care (POC) were evaluated recently during a meeting of experts in Vienna.

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Study

Link between blood sugar and brain cancer found

New research further illuminates the surprising relationship between blood sugar and brain tumors and could begin to shed light on how certain cancers develop. While many cancers are more common among those with diabetes, cancerous brain tumors called gliomas are less common among those with elevated blood sugar and diabetes, a study from The Ohio State University has found. The discovery builds…

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Don't turn a blind eye

Annual dilated eye exams key in preventing diabetic eye disease

Diabetic eye disease is the leading cause of blindness among people ages 40 to 60. The longer you have diabetes, the greater your likelihood of developing vision problems increases. Keeping blood sugar, blood pressure and cholesterol levels under control can help people with diabetes maintain good eye health. They must also have a dilated eye exam once a year, says Dr. Malav Joshi, an…

Developments in dressings and bedding

Little research has been carried out into new therapies for wound healing. As chronic wounds tend to be classed as side effects of other diseases, e.g. diabetes, they are often treated as trivial. However, the body's capacity to heal itself often does not set in for weeks.

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Laboratory adoption

POCT – a critical review and perspective

Not long ago, POCT was a specialist diagnostic discipline used by only few laboratory staff. This has changed considerably over recent years. Initially, the main focus had been on determining electrolytes, blood gases, blood clotting and blood count, but further parameters, such as kidney function, cardiac enzymes, urine tests and testing for autoimmune diseases have now been added. Whilst the…

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Heat therapy

Soaking in a hot tub has unexpected benefits, researchers find

According to new research, obese women with polycystic ovary syndrome (PCOS) may be able to improve their health outlook with a particularly enjoyable form of therapy: regular sessions in a hot tub. The research found that soaking in a hot tub several times per week for two months results in improved measures of cardiovascular health, beneficial changes in fat tissue and other improvements…

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Diabetes

Telemedicine could improve access to eye exam

Electronic eye exams could become popular in the U.S. among patients who see them as an easy way to visit the eye doctor. After a nationwide telemedicine diabetic screening program in England and Wales, for example, diabetic retinopathy is no longer the leading cause of blindness there.

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MRI & Liver

MRI leading the way in metabolic disease imaging

New MRI techniques are set to offer advances in the earlier detection of liver disease in patients. Radiologists are harnessing the potential of highly-targeted MRI, whilst exploring the imaging modality as a means of delivering non-invasive biomarkers, reducing the need for biopsy to measure treatment response.

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Diabetic biomarker test successfully verified

EKF Diagnostics announces that its newly introduced Glycated Serum Protein (GSP) LiquiColor® diabetic biomarker test has been verified for use on the Siemens Vista chemistry analyzer. In a scientific poster published by scientists at the Memorial Healthcare System, Hollywood, USA [1], it was demonstrated that EKF’s GSP assay enhances the versatility of the Vista system for the specialized…

Diabetes research

Healing burn wounds with cell therapy

An experimental treatment in mice allows the reprogramming of blood cells in order to promote the healing process of cutaneous wounds. This approach could prove to be beneficial in healing challenging wounds in diabetics and major-burn victims.

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Platform demonstrations

AEGLE webinars take a look at Big Data analytics in Healthcare

In February 20th and 22nd and March 15th 2018 AEGLE is launching a series of webinars with the objective of demonstrating how the final prototype of the AEGLE platform supports the use of big data analytics in healthcare. The tools and analytics that the AEGLE Platform supports can be used for both (clinical) research and clinical practice. The four demos that will take place online through a…

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In technology's firm embrace

AI could enhance or disrupt healthcare

Artificial Intelligence (AI) has enormous potential to revolutionise the delivery of healthcare, being able to remove the drudgery’ of routine tasks, join up fragmented care records, trigger alerts when abnormal results occur, speed-up the process of identifying clusters of patients by digging deep into electronic health records, and increase efficiency of healthcare staff resources.

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Phosphatidic acid phosphatase

A fat-regulating enzyme could hold the key to obesity and diseases

It had already been known that the enzyme known as phosphatidic acid phosphatase plays a crucial role in regulating the amount of fat in the human body. Controlling it is therefore of interest in the fight against obesity. But scientists at Rutgers University-New Brunswick have now found that getting rid of the enzyme entirely can increase the risk of cancer, inflammation and other ills.

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Under the skin

Handheld scanner reveals vascularization in psoriasis patients

A newly developed tissue scanner allows looking under the skin of psoriasis patients. This provides clinically relevant information, such as the structure of skin layers and blood vessels, without the need for contrast agents or radiation exposure. A team of researchers from Helmholtz Zentrum München and the Technical University of Munich (TUM) recently introduced the technology in ‘Nature…

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Sertraline usage

Standard antidepressant may be ineffective with chronic kidney disease patients

A clinical trial involving hundreds of participants has shown that one of the most frequently prescribed antidepressants may not benefit millions of patients who also have chronic kidney disease (CKD). “These results provide evidence that could change clinical practice,” said Dr. Susan Hedayati, Professor of Internal Medicine at UT Southwestern and first author of the study, which was…

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RUT -

A system of national quality registers, established in recent decades in Sweden's health and medical services, now numbers 64 registers. Along with three competence centres, these cover, for example, diabetes mellitus (NRD), dementia (SeDEM), Swedish intensive care (SIR) and acute coronary care (RIKS-HIA), and the Register Ulcer Treatment (RUT), which was added at the dawn of 2007. The latter has…

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Large study

Five novel genetic changes linked to pancreatic cancer risk

In what is believed to be the largest pancreatic cancer genome-wide association study to date, researchers at the Johns Hopkins Kimmel Cancer Center and the National Cancer Institute, and collaborators from over 80 other institutions worldwide discovered changes to five new regions in the human genome that may increase the risk of pancreatic cancer. The new findings represent one more step toward…

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Ophthalmology

Researchers explore way to reverse diabetic blindness

Johns Hopkins researchers have discovered a cell signaling pathway in mice that triggers vision loss in patients with diabetic retinopathy and retinal vein occlusion – diseases characterized by the closure of blood vessels in the retina, leading to blindness. In experiments that suppressed vascular endothelial growth factor (VEGF) in the eye, researchers were able to re-establish normal blood…

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7 tesla MRI

A new technique for dilated cardiomyopathy

UK researchers are working on a more precise imaging technique for dilated cardiomyopathy that may lead to more effective treatments. A study from the University of Oxford Centre for Clinical Magnetic Resonance Research (OCMR), part of the Division of Cardiovascular Medicine at the university, has demonstrated how the next generation of MRI scanners can work to measure heart conditions in dilated…

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Old technique & new technology

Optoacoustics: the sound of cells

For centuries, hands, eyes and ears were the physicians’ most important instruments when it came to detecting and diagnosing disease. Today, one of the traditional techniques, percussion, is being revived, supported by state-of-the-art technology and dressed in a new name: optoacoustics. In one of the most exciting visionary ideas in modern healthcare short laser pulses (optics) are transmitted…

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Major success

Colorectal cancer deaths go down 7% - but it's too early to celebrate yet

The decline in cancer of the intestines – colorectal cancer – is one of the major success stories of the past 30 years in Europe say researchers, as they predict that in 2018 death rates from the disease will continue to fall by around seven per cent compared to 2012. In a study published in the leading cancer journal Annals of Oncology, researchers predict that death rates in the European…

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MRI vs. Alzheimer's

Seeking leaks in the blood-brain barrier

‘With our new MRI method, we can finally visualise tiny leaks in the blood-brain barrier. They shed light on the vascular contribution to dementia and may indicate Alzheimer’s disease. However, the MRI scan is only a tool to diagnose cerebrovascular damage. We have not yet found a cure for Alzheimer’s,’ confirms Walter H Backes, medical physicist and professor at Maastricht University…

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Professional standards

The role of sonographers: future professionals across Europe?

Ultrasound is often the first line of imaging used in the diagnostic pathway of a patient’s journey into hospital. Additionally, the increased prevalence of chronic conditions and changes in the demographics of the general population has led to an increased demand for ultrasound. Fast-growing advances in technology also shift ultrasound into a more prominent role in patient diagnosis and…

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Future changes

Laboratory medicine is an interdisciplinary subject

‘Lab medicine connects’ is the congress theme of the German Congress of Laboratory Medicine and reflects the fact that laboratory medicine is an interdisciplinary subject like no other and connects those who are involved in medicine across disciplines. It works almost imperceptibly in the background, hardly noticed by patients. European Hospital spoke with this year’s Congress President,…

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POC

The next-generation RAPIDComm System

Siemens Healthineers announced today it released a major software upgrade for the RAPIDComm Data Management System (V6.0), an informatics solution to centrally manage in vitro diagnostics analyzers and operators at the point-of-care (POC). In addition to the system’s enhanced productivity and performance features, RAPIDComm V6.0 now connects with POC cardiac devices.

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Animal testing

Scientists identify protein linked to chronic heart failure

Researchers in Japan have identified a receptor protein on the surface of heart cells that promotes chronic heart failure. The study, “Corticotropin releasing hormone receptor 2 exacerbates chronic cardiac dysfunction” suggests that inhibiting this protein could help treat a disease that affects more than 20 million people worldwide.

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Psychological consequences

Cortisol excess hits natural DNA process hard

High concentrations of the stress hormone, Cortisol, in the body affect important DNA processes and increase the risk of long-term psychological consequences. These relationships are evident in a study from the Sahlgrenska Academy on patients with Cushing’s Syndrome, but the findings also open the door for new treatment strategies for other stress-related conditions such as anxiety, depression…

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Wisdom tooth indeed

This electronic high-tech tooth could predict diseases

An interdisciplinary team of researchers from Washington University School of Medicine in St. Louis and the School of Engineering & Applied Science is redefining the notion of a wisdom tooth. The team is developing a smart-tooth technology that could someday be used to detect early signs of certain diseases in high-risk patients by analyzing saliva or gingival crevicular fluid.…

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New approach

Starving liver cancer

Scientists at the University of Delaware and the University of Illinois at Chicago have found a new way to kill liver cancer cells and inhibit tumor growth. First, they silence a key cellular enzyme, and then they add a powerful drug. They describe their methods in a new paper published in Nature Communications. This research could accelerate the development of new treatments for liver cancer,…

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Sugar and health

The not so sweet side of Christmas

A new video by the University of Warwick highlights a bitter side to our sugar consumption at Christmas. The short film highlights how excessive consumption of sugar can affect our health – and how the sugar trade in the past and today has caused inequality and bloodshed. Today Britons eat too much sugar, on average 10 per cent of our daily calories come from sugar which is equivalent to 60 g…

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It's in the air

Higher air pollution in cities tied to higher mortality

New research presented at APHA’s 2017 Annual Meeting and Expo examined the burden of air pollution and its association with mortality in Chinese cities. The study by researchers at Drexel University Dornsife School of Public Health showed a significant correlation between higher air quality index concentrations and higher mortality rates. The study is the first to provide strong evidence of the…

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Nationwide cohort study

Can an aspirin a day keep liver cancer away?

A new study presented this week at The Liver Meeting held by the American Association for the Study of Liver Diseases found that daily aspirin therapy was significantly associated with a reduced risk in hepatitis B virus‐related liver cancer. Past research suggests that daily aspirin therapy — which is often prescribed to prevent cardiovascular disease — may also prevent the development of…

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Heart Attacks

Potential Breakthrough in Determining Who’s at Risk

Researchers are revisiting their views on the relative dangers soft and hard atherosclerotic plaque deposits pose to heart health. Findings of a new study by researchers at the Intermountain Medical Center Heart Institute may be a “game-changer” for determining who’s at risk of a heart attack, they say.

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Is the "American Dream" slipping away?

Drugs, alcohol and suicides contributing to alarming drop in US life expectancy

Drugs, alcohol and suicides are contributing to an alarming drop in US life expectancy, particularly among middle-aged white Americans and those living in rural communities, warn experts in The BMJ. Steven Woolf at Virginia Commonwealth University and Laudan Aron at the Urban Institute in Washington DC, argue that the ideal of the “American Dream” is increasingly out of reach as social…

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Cardiovascular MR

Standard medical tests miss nearly two-thirds of heart attack diagnoses

Standard medical tests miss nearly two-thirds of heart attack diagnoses, reveals research presented at CMR 2018. “Unrecognised MI has a poor short-term prognosis but until now the long-term outlook was unknown,” said lead author Dr Tushar Acharya, a cardiologist at the National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, US. “This study investigated long-term…

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Neurotransmissions

Nanosensors uncloak the mysteries of brain chemistry

Nanosensors are incredible information-gathering tools for myriad applications, including molecular targets such as the brain. Neurotransmitter molecules govern brain function through chemistry found deep within the brain, so University of California, Berkeley researchers are developing nanosensors to gain a better understanding of exactly how this all plays out. During the AVS 64th…

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The UK’s one million undiagnosed diabetics

At the end of June a shocking new estimate was released in the UK regarding the number of people unwittingly going about their lives without knowing they are type 2 diabetics – there are just over a million of them. How will the country cope with this discovery and its present diabetic population?

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“Get Serious” needs your support

Now firmly established within the social media world - with over 10,000 Facebook fans, over 2,500 followers on Twitter, and many more supporters across other sites - we need our online supporters to help with our 'Get Serious' campaign.

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EASD 2010 review

7,000 people from 120 countries met in Stockholm this September to hear international experts discuss the progress, solutions and challenges of one of our greatest healthcare burdens. Prevention, self-monitoring, surgery, guidelines, economic problems, drug-safety, and co-morbidities – these are just a few of the problems associated with the care of about 55 million diabetics in Europe.

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Scientists tissue-engineer part of human stomach

Researchers at Cincinnati Children’s Hospital Medical Center grew functional stomach and intestinal tissues to study diseases and new drugs. They use pluripotent stem cells to generate human stomach tissues in a petri dish that produce acid and digestive enzymes.

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Annual conference

The role of cardiology at the extremes

Cardiology at the extremes will be the key theme at the British Cardiovascular Society annual conference in Manchester in June. Topics covered include reflections in cardiology and space travel, physiological challenges associated with living under extreme environmental conditions and polar expeditions. Report: Mark Nicholls

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World Brain Day

Stroke is over (if you want it)

The fourth World Brain Day (July 22) revolves around stroke – how to detect it, how to prevent it, how to treat it. Raad Shakir, president of the World Federation of Neurology (WFN), seizes the opportunity to raise awareness about a disease that is becoming more common globally – but also preventable to a large extent.

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Immunological memory

Our brains 'remember' inflammation and diseases

Inflammatory reactions can change the brain’s immune cells in the long term – meaning that these cells have an ‘immunological memory’. This memory may influence the progression of neurological disorders that occur later in life, and is therefore a previously unknown factor that could influence the severity of these diseases. Scientists at the German Center for Neurodegenerative Diseases…

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Protein quality control system

Cellular power outage

A common feature of neurodegenerative diseases are deposits of aggregated proteins in the patient's cells that cause damage to cellular functions. Scientists report that, even in normal cells, aberrant aggregation-prone proteins are continually produced due to partial failure of the respiratory system. Unless they are removed by degradation, aggregates accumulate preferentially in the…

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Regeneration

Immune cells help rebuild damaged nerves

Immune cells are normally associated with fighting infection but in a new study, scientists have discovered how they also help the nervous system clear debris, making way for nerve regeneration after injury. In a study published in the Journal of Neuroscience, researchers from Case Western Reserve University School of Medicine showed certain immune cells—neutrophils—can clean up nerve debris,…

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IT solutions

Big data: Utilising potential where it presents itself

Useful IT tools are abundant in today’s laboratories – ranging from software to evaluate analyses to specialist software for quality control, and middleware linking different devices. However, all these tools generate data, the adequate utilisation of which is not an easy task, said Udo Margraff, CEO of Laboratoires Réunis in Luxembourg, during our European Hospital interview. Among other…

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It's dangerous to go alone

Why social isolation can bring a greater risk of illness

Social isolation has been linked to a wide range of health problems, as well as a shorter lifespan in humans and other animals. In fact, during a U.S. Senate hearing on aging issues this spring, a representative for the Gerontological Society of America urged lawmakers to support programs that help older adults stay connected to their communities, stating that social isolation is a “silent…

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Proteomics International Laboratories Ltd.

Predictive test for diagnosis of diabetic kidney disease

Life sciences company Proteomics International Laboratories (ASX: PIQ) is pleased to announce that it has produced and validated a predictive test for the diagnosis of diabetic kidney disease (DKD). The test, called PromarkerD, is the world's first proteomics-derived predictive (prognostic) test for the diagnosis of DKD, and represents a global breakthrough in the diagnosis and treatment of the…

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Cell signals

Wound healing: more complex than you think

In a sharp and pointy world, wound healing is a critical and marvelous process. Despite a tremendous amount of scientific study, many outstanding mysteries still surround the way in which cells in living tissue respond to and repair physical damage. One prominent mystery is exactly how wound-healing is triggered: A better understanding of this process is essential for developing new and improved…

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Profession

The growing role of a hospitalist

New words are consistently spun out in the USA and frequently assimilated into ‘American English’. Take the term ‘hospitalist’ (little used in European English), which was coined by the renowned academic physician Robert M Wachter (University of California, San Francisco) and his colleague Lee Goldman, in an article published in the New England Journal of Medicine in 1996. Lisa Chamoff…

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ESC Congress 2017

Entering the future of cardiology

With 4,500 accepted abstracts, 600 sessions and 30,000 expected attendees, ESC Congress 2017 is undoubtedly the world’s largest cardiovascular event. On healthcare-in-europe.com, Dr Stephan Achenbach, Congress Program Committee Chairperson, gives an overview of issues and events unfolding in Barcelona from August 26-30.

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Dysglycaemia

Dysglycaemia is a new term in critical care that recognises the vital importance for glucose monitoring of patients in the intensive care unit (ICU). Beyond the clinical consensus over this word for grouping critically ill patients with hyperglycaemia, hypoglycaemia or high blood sugar, there is no broad agreement on how best to manage these patients. Report: John Brosky.

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Exhibition

Progress in medicine presented at Bulmedica/Buldental 2018

New products and technologies in medical practice expect the specialists of the leading international exhibition Bulmedica/Buldental from 16 to 18 May at Inter Expo Center. This year, the medical profile of the exhibition will focus on the progress in imaging, physiotherapy, aesthetic medicine. Once again Bulmedica/Buldental will be a platform to keep an eye on the tendencies, a meeting point of…

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Abdominal fat

For women with kidney cancer, belly fat matters

Belly fat affects the odds of women surviving kidney cancer but not men, according to a new study by researchers at Washington University School of Medicine in St. Louis. Half of female kidney cancer patients with substantial abdominal fat at the time of diagnosis died within 3 1/2 years, while more than half of women with little belly fat were still alive 10 years later, the researchers found.…

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Physicians protest

Overworked family doctors sound the alarm

Three quarters of Dutch general practitioners (GPs: family doctors) experience an increasing work pressure, according to a recent survey of the National Association of General Practitioners (LHV). Especially evening, night and weekend services at GP Emergency Posts (Dutch: HAP) are found to be heavy duty, in addition to their daily practice.

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Chronic disease

There is a global shortage of doctors that is getting worse every year. With the demographic shift in many countries from a predominantly young to an increasing aging population, a steep increase in chronic disease is occurring.

Diabetics and drug-eluting stents

Boston Scientific Corporation has announced results from a pooled analysis of patients from its TAXUS IV and TAXUS V randomised clinical trials to compare the safety and efficacy of the TAXUS Express Paclitaxel-Eluting Coronary Stent System in diabetic versus non-diabetic patients.

Primary prevention of CVD: Challenges and Achievements

Lifestyle and risk factor results show that recommended scientific guidelines form a contrast to what is achieved in daily practice in high risk individuals in primary prevention of CVD. Together with its partners the ESC demands a comprehensive and multisdicplinary primary prevention programme involving the high-risk population, their GP's and other health professionals, a health insurance…

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Beckman Coulter – HbA1c Advanced

diabetes mellitus.National Glycohemoglobin Standardization Program (NGSP) certified/DCCT standardized and precise, providing clinically relevant results for diagnosing and monitoring diabetesUnaffected
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Sarstedt – S-Monovette GlucoExact

immediately for up to 96 hours at room temperature.It meets the Gestational Diabetes Guidelines of the German Diabetes Association (DDG) and the German National Disease Management Guidelines (NVL) for type
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Initiative

Knowledge dissemination key to defeating cancer?

Half of cancers can be avoided if institutions would exchange knowledge, according to Joxel García, executive director of the University of Texas MD Anderson Cancer Center in Houston, who opened the Center’s meeting in Madrid in October 2016. Technology has progressed enormously and there has never been that much knowledge of cancer to prevent it and find treatment tools.

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Beckman Coulter – HbA1c Advanced

diabetes mellitus.National Glycohemoglobin Standardization Program (NGSP) certified/DCCT standardized and precise, providing clinically relevant results for diagnosing and monitoring diabetesUnaffected
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Arrays to detect genomic disorder

Roche reports that, using its NimbleGen CGH arrays, researchers* have identified a recurrent reciprocal genomic rearrangement of chromosomal region 17q12 in foetal samples with congenital anomalies that is also associated with paediatric renal disease and epilepsy.

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Warning

Obesity needs urgent action

The leading organisation responsible for research into obesity in Europe has warned that unless something is quickly done to tackle the region’s rising obesity epidemic, it is going to have a devastating effect on healthcare costs and productivity.

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Insulin capsules - a promising alternative to injections

Researchers from the Robert Gordon University in Aberdeen, UK, presented a study at The British Pharmaceutical Conference, held from 10th to 12th September, 2007, at Manchester Central, showing that a chemical coating is able to encapsulate and protect insulin against enzymes that usually break down the hormone in the gastrointestinal tract.

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Bone health

Osteoporosis defined: causes, symptoms and treatments

Weak, easily broken bones are an epidemic in the United States. They’re often tied to osteoporosis, a disease that causes bones to degenerate over time. This makes them less flexible, more brittle, and easier to break. According to the International Osteoporosis Foundation, more than 44 million Americans aged 50 and older either have or face the threat of developing osteoporosis due to low bone…

Near-patient testing (NPT)

Near-patient testing (NPT) is any analytical process performed for, or by, a patient outside the traditional clinical laboratory. By Manole Cojocaru MD PhD, scientific consultant at ROMAR Medical-Laboratory Colentina, Bucharest

Concern over insulin drug withdrawal

Drug company Novo Nordisk’s decision to pull its Mixtard 30 insulin drug from the UK could add almost €11 million to the NHS drugs bill in England alone, according to an editorial in the Drug and Therapeutics Bulletin (DTB). This decision could also leave thousands of patients dependent on others to help them take their insulin, said DTB, as it launched its Don’t Drop Mixtard 30 campaign in…

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Civilisation Diseases breaking economic growth

More than 63% of all deaths in the world are caused by so- called non-communicable diseases. In the WHO-region of Europe it’s even higher – 86%. The direct and indirect economic costs are huge – to the point of posing a real threat to growth in crisis-hit economies. Therapy alone is not enough, World Bank strategist Dr. Armin Fidler told the European Health Forum Gastein. Effective…

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The AACC Annual Meeting & Clinical Lab Expo

The American Association for Clinical Chemistry (AACC) hosts its 2009 meeting in conjunction with the Canadian Society of Clinical Chemists. Along with this, a high European participation is on the cards. "We are pleased that so many peers from Europe join us each year, and that our European colleagues lead many of the important scientific sessions," said Barbara Goldsmith PhD, current AACC…

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Treating obesity surgically

Professor Rudolf A Weiner, head of the surgical department at Sachsenhausen Hospital, Germany, reports that some developing procedures result not only result in weight loss but also in the systematic elimination of metabolic disorders, and that many new developments in the field promise hope for both the obese and their doctors

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Compelling cohorts

Population imaging: Big Data will boost disease prediction

Population imaging is key to determining disease prediction and risk prevention, and Big Data will be key to extracting information and drawing analysis from imaging results, experts highlighted during the annual meeting of the European Society of Magnetic Resonance in Medicine and Biology (ESMRMB) held in Barcelona in October. Interest in cohort studies has been increasing over the years and…

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Biomarker validation

Plodding toward a pancreatic cancer screening test

Pancreatic cancer is one of the most deadly types of malignancies, with a 5-year survival rate after late diagnosis of only about 5%. The majority of patients—about 80%—receive their diagnosis too late for surgery. The disease spreads quickly and resists chemotherapy. In short, there is an urgent need for diagnostic tools to identify this cancer in its earliest stages.

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Home care

Pioneering NHS ‘test beds’

A ‘technology’ project to modernise healthcare for patients with long- term medical conditions is being trialled in the United Kingdom in seven ‘test bed’ initiatives. Test Beds, a term used to describe a technology project resulting from collaborations between the UK’s National Health Service (NHS) and international innovators, aims to harness technology to address issues facing…

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Telehealth study

England’s Florence looks like a winner

Given the increasing focus on telehealth and telecare services aimed at improving long-term patients’ living conditions and save costs, numerous pilots in various countries have been conducted for proof of concept purposes. Among these, the United Kingdom’s ‘Whole System Demonstrator’ (WSD) programme is the largest randomised controlled trial. Set up by the English National Health Service…

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Bariatric surgery: A last resort -- or the only way to go?

More than half of the European population is overweight, or worst, obese. When diet and lifestyle changes do not result in permanent weight reduction in obese patients, bariatric surgery is now considered a final option. But, that’s far too late, says Professor Rudolf A Weiner, head of the surgical department at Sachsenhausen Hospital in Frankfurt/Main, Germany, and President of the German…

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The role of exercise training in cardiovascular health

Western societies are struggling to pay for their ever increasing medical budgets. In the US up to 393 billion US-$ were spent in 2005 for cardiovascular diseases alone. Based on epidemiologic studies in primary prevention it is reasonable to estimate that 30% of coronary heart disease and stroke could be prevented by 2.5 hours of brisk walking per week.

Patient monitoring devices

In 2009, the continuous glucose monitoring (CGM) market earned manufacturers $23.5; this is forecast to reach $52.0 million in 2016, according to a new analysis from Frost and Sullivan (F&S). For the study the markets covered by region are Benelux, Germany, France, Italy, Scandinavia, Spain and the United Kingdom.

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Management II

Coming of age with a chronic disease

During the transition from child to adult many teens with chronic diseases somehow slip through the healthcare cracks between paediatric and adult medicine. Compliance deteriorates, regular check-ups are missed – an international problem, as many studies indicate. A promising programme, launched in Berlin, helps teens to manage this difficult change. Report: Bettina Döbereiner

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Healthy or diseased?

The ratio between the concentrations of metabolites may give the answer to the question. Researchers at the Helmholtz Zentrum in Munich demonstrated the proof of principle. They identified diabetic or healthy mice by biomarkers they analyzed only by bioinformatics. Metabolomics might permit a promising tool for pre-clinical investigation of effects and side effects of new drugs, they say.

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One in six people will have a stroke, but most strokes can be prevented

The theme of this year's World Stroke Day on 29 October is "One in Six", referring to the facts that one in six people will have a stroke at some point in their lifetime, and that a stroke will be the cause of someone's death every six seconds. These, says the World Stroke Organization (WSO), are everyday people leading everyday lives, but around 85% of them will have risk factors…

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Hard-to-heal wounds

In `Hard-to-heal wounds: a holistic approach´ a paper produced by the European Wound Management Association (EWMA), the authors analyse the calculation of treatment costs, based on international examples, and point out problems associated with a clear definition of the term treatment costs. They also emphasise the importance of the addition of the term holistic approach.

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It's official – chocolate linked to heart health

High levels of chocolate consumption might be associated with a one third reduction in the risk of developing heart disease, finds a study published on bmj.com. The findings confirm results of existing studies that generally agree on a potential beneficial link between chocolate consumption and heart health. However, the authors stress that further studies are needed to test whether chocolate…

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State of the art technology for biomedical imaging

A convenient technology to quantify three-dimensional (3D) morphological features would have widespread applications in biomedical research. Now, researchers from Umea University in Sweden presented a new method for 3D imaging and quantification of biological preparations ten times larger than the limit for traditional confocal microscopes.

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Early Health - Investment or Cost?

Early Health, i.e. the early detection of diseases, will have to move into the centre of attention - this is the result of a survey by Total Healthcare Solutions (THS). Dr Susanne Michel, Associate Director at THS, underlines that in the future prevention will have to be considered an investment in healthcare rather than a mere cost factor. Decision makers from politics and the healthcare system…

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VenomKB

World's first therapeutic venom database

What doesn't kill you could cure you. A growing interest in the therapeutic value of animal venom has led a pair of Columbia University data scientists to create the first catalog of known animal toxins and their physiological effects on humans.

Standardised algorithms and protocols for diabetic in-patients

Dr Susan S Braithwaite, a visiting clinical professor in endocrinology at the Department of Medicine, University of Illinois, Chicago, specialises in the management of hyperglycaemia among hospitalised patients. Hyperglycaemia, the presence of an abnormally high concentration of glucose in the blood, is a common occurrence in adults who are hospital in-patients, especially among diabetic…

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POCT

This market will boom

The turnover in POCT diagnostics will continue to increase substantially according to participants in an ‘In Vitro Diagnostic Products’ meeting held in Toronto, Canada last October. Sponsored by the German Institute for Standardisation, the event included participation by the DIN Standards Committee Medicine (NAMed; NA 063) and the Working Committee on Point of Care Testing (POCT) (NA…

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The 16th IFSO World Congress

September saw the international crème de la crème of bariatric surgery descend on Hamburg for the 16th World Congress of the International Federation for the Surgery of Obesity and Metabolic Disorders (IFSO 2011). Among their discussions: new minimally invasive procedures, the importance of aftercare and the lack of recognition of the importance of surgical treatment of the severely obese in…

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Morbid obesity in Europe

Prevalence of adult obesity has increased three-fold since 1990. The prevalence of childhood obesity has increased ten times since 1970. In Europe, almost 50% of adults and over 20% of children are overweight. A third of these are obese. Conservative estimates show that, in Europe, about 100 million adults and 10 million children are obese. Obesity is accountable for c. one million deaths…

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Computer-assisted coding

Every hospital does it, but how accurately and consistently coding is done has a major effect on the quality of treatment and also on the bottom line. Traditionally so-called ‘coders’ determine which code to apply for a specific medical service.‘ Report: Cornelia Wels-Maug

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Procurement

Fundus screening enters shopping centres

Telemedicine is taking strides throughout Europe. While in Germany telemedicine projects appear to be off to a slow start (see the electronic health card), in other countries progress is going full throttle. In September, at the German-Dutch symposium ‘Using optimisation potential: Telemedicine and procurement management’ a number of Dutch approaches were presented. Report: Sylvia Schulz

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Obesity from the lab point of view

Over the last 25 years overweight and obesity have become a global epidemic. According to WHO figures, at least 400 million adults are obese worldwide. Part of this phenomenon relates to lifestyle changes - lack of exercise, wrong eating habits - whereas genetic factors also play a role (according to twin studies, the determination of obesity is 70% nature and 30% nurture).

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Vielversprechende Forschungsergebnisse zu Herz-Kreislauf-Erkrankungen

Das Center for Cardiovaskular Research (CCR) an der Berliner Charité konnte sich durch vielseitige Grundlagenforschung über die deutschen Landesgrenzen hinaus bereits einen Namen machen. Nun stellt das CCR in einem aktuellen Zwischen- bericht unter anderem vielversprechende Ent- wicklungen einer neuen Medikamentenklasse bei Endorganschäden und die Erforschung der Blutgefäßbildung bei…

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MEDICA 2008 opens its doors

When from 19 to 22 November the world's largest medical fair takes place in Dusseldorf, the entire city is in a kind of emergency state: hotels are bustin' out of their seams, traffic periodically comes to a standstill and at night exhibitors and visitors alike crowd the narrow streets of the Altstadt and the fancy hotel bars and enjoy whatever entertainment North Rhine-Westphalia's capital has…

Further reports from the ACC 57th Scientific Session

A five-year study of 516 participants with coronary artery disease showed that patients who reduced their anxiety levels or kept them steady were 60% less likely to have a heart attack or die compared with those who had increased anxiety levels.

New cancer therapy to fight cardiovascular diseases?

New drugs that are helping fight a multi-front war on cancer may do the same for cardiovascular disease, Medical College of Georgia researchers said. Cancer and cardiovascular disease, both among top U.S. killers, share inflammation as a cause. Heat shock protein 90 inhibitors as a treatment could become additional common ground, said Dr. John Catravas, director of MCG's Vascular Biology Center.

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Bayer HealthCare glucose monitoring system climbs the top

Bayer loves sports. Therefore it developes medical devices to work under extremes. Recently extrem-athlete and diabetic Geri Winkler conquered the Seven Summits - a group of mountains comprising the highest peaks on each of the seven continents. The blood glucose monitoring system from Bayer HealthCare is always with him.

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When overweight kids become heart condition adults

A modern-day childhood totally differs from what was common just a few decades ago. It is mostly spent sitting -- at school desks, in front of TV screens or before computer monitors – all combined with the sweet temptations of the kid’s food industry. According to a WHO worldwide estimate, an estimated 10% of school-age children between five and 17 years old are overweight or obese. The…

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Siemens Healthineers – DCA Vantage Analyzer

Siemens HealthineersSiemens Healthineers – DCA Vantage Analyzer Dimensions: 287 × 254 × 277 mm (w × h × d)Weight: 3.88 kgHighlights:The DCA Vantage Analyzer makes in-office diabetes testing easy
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Lifotronic – H9 Hemoglobin Analyzer

Lifotronic Technology Co., LtdLifotronic – H9 Hemoglobin Analyzer Highlights:Reliable partner for diabetes testIon-Exchange HPLCGold standard methodology for HbA1C72 seconds / test (Fast mode)High
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Lifotronic – H8 Hemoglobin Analyzer

Lifotronic Technology Co., LtdLifotronic – H8 Hemoglobin Analyzer Highlights:Reliable partner for diabetes testIon-Exchange HPLCGold standard methodology for HbA1C130 seconds / test (Variant mode)High

Urinalysis strip test

Siemens new Clinitek Micro-albumin 9 Urinalysis Strip is now available in Europe. The strips, which can be used on the firm's Clinitek Status analyser, or the Clinitek Advantus analyser, provide nine tests to detect and monitor kidney disease.

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Researchers Find Protein 'Switch' Central to Heart Cell Division

In a study that began in a pair of infant siblings with a rare heart defect, Johns Hopkins researchers say they have identified a key molecular switch that regulates heart cell division and normally turns the process off around the time of birth. Their research, they report, could advance efforts to turn the process back on and regenerate heart tissue damaged by heart attacks or disease.

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Neurological diseases on the rise

„Diseases of the nervous system and the brain occur more frequently than cancer. According to recent calculations of health care costs, they represent a burden of 386 billion euros a year on European economies,“ says Prof. Gérard Said, newly elected president of the European Neurological Society (ENS) at the annual meeting in Berlin, Germany. „This is often greatly underestimated.“

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World Stroke Day 2009: Learning the risks for stroke - and taking action

Stroke accounts for almost 6 million deaths each year and ranks second only to heart disease as the world's leading cause of death. The theme of this year's World Stroke Day on 29th October is "What can I do?". As the World Stroke Organization says, everyone can do something: learn to recognise symptoms and take action, learn to recognise the risk factors and take action.

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Monitoring of Surgical Bypasses

The aortocoronary bypass is an important surgical method for multivessel coronary revascularization, especially in the presence of complex lesions and in diabetic patients. It is can improve the prognosis of patients with three vessel disease and with left ventricular dysfunction1 . With regard to the type of graft used, bypasses are split into venous and arterial types. The use of venous…

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Bilateral initiation

Renowned French and German cardiovascular researchers gathered in October at the French Embassy in Berlin for a one-day symposium entitled ‘The Frontiers of Cardiovascular Research: From Basic Concepts to Novel Approaches in Therapy and Prevention’

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Luhacovice

Admittedly not one of the easiest names to pronounce but a name to note: Luhacovice in the Czech Republic.

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Genom

I looked into my genes and changed some habits

“These dates we have access to a lot of genetic information which had previously not been available to us. For the individual, this can provide options for action with regards to leading a healthier lifestyle or to try and prevent diseases,” knows Dr. Theodor Dingermann. The senior professor of the Goethe University in Frankfurt am Main has had his own genome decoded. In parts, the result…

Spotlight Cholesterol: the role of diet, statins and genetics

The inverse epidemiological association between serum levels of HDL-C and risk of coronary artery disease (CAD) is graded and has been validated in multiple studies. However, there is remaining controversy whether a low HDL-C should not predominantly be considered a marker of poor lifestyle (obesity, lack of exercise, hypertriglyceridemia, diet, etc.), rather than a primary causal agent for…

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Serving and improving Middle East healthcare

The 2nd Hospital Build Middle East Exhibition & Congress (1-3 June. Dubai) aims to draw together the investors, commissioners, backers and managers of major healthcare building projects, as well as suppliers of services in planning, design, building, operations, management and refurbishment.

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Hot topic II

News from Israel

CNOGA Medical Ltd. is a leading developer and manufacturer of innovative e-health ecosystems for non-invasive, pain-free bio-marker monitoring and cloud-based ecosystem technology. At MEDICA CNOGA Medical presents its new Ecosystem Infrastructure of Non-Invasive Hemodynamics, Blood parameters & Blood gases Monitoring Devices, Cloud-Based Platform and Mobile Application.

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Philips and the World Association of Sleep Medicine join together

Royal Philips Electronics will join with the World Association of Sleep Medicine (WASM) as an official sponsor of World Sleep Day 2012. This year’s theme– ‘Breathe Easily, Sleep Well’ – centers on raising awareness of sleep disorders that affect a person’s breathing, such as obstructive sleep apnea (OSA).

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Genome Structural Variation Consortium used Roche technology

Roches NimbleGen´s CGH microarray platform was used to generate the highest-resolution map of human genome copy number variation. Recent advances in microarray technology have led to the discovery of extensive copy number variation in the human genome, including DNA copy number gains (duplications), losses (deletions), and multiallelic or complex rearrangements.

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Fast, accurate and convenient

New test identifies early sepsis

A newly launched test enables the quantitative determination of PCT in serum samples, EDTA or lithium heparin plasma samples by latex enhanced immunoturbidimetric methodology. The Stanbio Chemistry Procalcitonin (PCT) LiquiColor Assay was launched by EKF Diagnostics, based in Cardiff, Wales, which explains: ‘Procalcitonin is a marker for bacterial infection and sepsis and has been recognised as…

Cardiovascular disease

Countries in the European Union spent €169 billion in 2003 on cardiovascular disease (CVD), according to research from a team at the Health Economics Research Centre, Department of Public Health, University of Oxford, England, just published on-line by the European Heart Journal.

Staphylococcus aureus

Women more likely to die within 30-days from bacterial blood infection

Clinicians around the world have long suspected that bacteraemia due to Staphylococcus aureus has a worse outcome in women compared to men, but direct evidence has been elusive. A study just published confirms that significantly more women than men diagnosed with Staphylococcus aureus bacteraemia (SAB) – a blood infection of the common bacteria – die within 30 days.

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Integration

Cookbook for large scale coordinated care

Royal Philips and its ACT-program consortium partners today announced the debut of a ‘cookbook’ outlining key enablers necessary to scale connected care and telehealth programs. The cookbook is the result from a two-and-a-half year scientific evaluation of data from different connected health programs in five European regions. It provides new insights that apply across the EU on why certain…

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Non-invasive

Good news for diabetics, cardiology patients and caretakers

At this year’s MEDICA, CNOGA Medical Ltd. will be introducing its new line of non-invasive, pain-free patient vital signs monitoring TensorTip™ devices, and presenting its new Singular™ platform, a secure cloud-based ecosystem infrastructure platform as well as its new mobile application for sending results to physicians, friends and caretakers. CNOGA’s easy-to-use, portable devices are…

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Technology

ProMRI Technology allows 3T scanning

Cardiovascular technology specialist Biotronik has launched a new series of single and dual chamber implantable cardioverter defibrillators (ICDs) and cardiac resynchronisation therapy defibrillators (CRT-Ds). ‘The Iperia/Itrevia/Inventra series gained CE approval in July 2014 and marked its first implantations worldwide in mid-July,’ the multinational biomedical technology firm reports.

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Multiple sclerosis

Multiple sclerosis (MS) – the inflammatory condition in the central nervous system (CNS) – leads to scarring, with several scars forming lesions, also called plaques. Although long assumed that only white matter is involved, this is increasingly questioned.

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Molecular diagnostics

Research in the field is booming thanks to newly arriving methods to identify gene sequences. Scientists are interested in a wide range of issues from disease-relevant variations of human genetic information to the detection of viral genetic material that supports therapies. Several highlights of current research were presented this spring at the 9th International Symposium on Molecular…

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The Renewing Health European project

Renewing Health is the Veneto Region’s response to the third Call of Proposals by the European Information Communication Technology Policy Support Programme (ICT-PSP). The project, which falls under the ICT-PSP financing plans, aims to facilitate the use of ICT-based solutions and services for citizens, the government, and businesses, as well as aiding their diffusion throughout Europe.

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India's world experts on TB

Every three minutes, two people living in India die of tuberculosis. This equates to approximately 370,000 deaths each year, and a staggering economic toll: an estimated US$300 million in direct costs and US$3 billion in indirect costs.

European Practice Assessment wins Health Award 2009

The "European Health Award" presented this year at the European Health Forum Gastein (EHFG) goes to the European Patient Assessment (EPA) project. EPA is designed to improve the exchange of knowledge and experience by practical physicians in the area of primary care. Cross-border healthcare initiatives are distinguished every year with the European Health Award.

Changing approaches to wound management

In recent years wound management has been primarily nurse-led, and not benefited from a multi-disciplinary approach. This must change, said Madeleine Flanagan, Principal Lecturer at the University of Hertfordshire's school of Post Graduate Medicine in the faculty of health and human science, where she runs the MSc in Dermatology and an MSc in Skin Integrity; she is also Principal of the European…

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At home genomic tests for disease risk may be premature

The recent marketing of "at home" genomic tests for disease risk may be premature, according to Dr. Kenneth Offit, MD, MPH, Chief of the Clinical Genetics Service at Memorial Sloan-Kettering Cancer Center (MSKCC). "Health professionals are now faced with the prospect of their patients coming to the office, a DNA profile in hand, asking for preventative management tailored to their…

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CLINICIP

Presented during a symposium at Langenbeck-Virchow-Haus, in Berlin, the European CLINICIP research project aims to develop a method to improve glycaemic control during intensive care and provide a low-risk monitoring and control system that can control the metabolism of the critically ill

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Hypertension worldwide

Countries vary widely in their capacity to manage hypertension, but globally the majority of diagnosed hypertensives is inadequately controlled. Not treated it can cause cardiovascular disease (CVD), myocardial infarction and stroke. According to the WHO, hypertension is estimated to cause 4.5% of the current global disease burden and is as prevalent in many developing countries as in the…

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Infection control

Scientists gain ground against resistance

The mechanism by which drug-resistant bacteria maintain a defensive barrier has been identified by researchers at England’s University of East Anglia (UEA) and their findings could result in a new wave of drugs that can bring down those defensive walls rather than attack the bacteria – thus they may not develop drug-resistance at all.

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Fraud

Fighting against counterfeit medicine

Around the world, especially in developing nations, counterfeit medicines are a real problem. Until now, in many countries there hasn't been a standard protocol to conduct investigations and pursue prosecution. New research, led by Michigan State University, is providing the foundation to apply criminology theory to preventing the production and sale of fake and substandard medicines.

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Bioengineering

Squeezing cells into stem cells

École polytechnique fédérale de Lausanne (EPFL) scientists have developed a new method that turns cells into stem cells by "squeezing" them. The method paves the way for large-scale production of stem cells for medical purposes.

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The role of the microbiota in preventing allergies

The human body is inhabited by billions of symbiotic bacteria, carrying a diversity that is unique to each individual. The microbiota is involved in many mechanisms, including digestion, vitamin synthesis and host defense. It is well established that a loss of bacterial symbionts promotes the development of allergies. Scientists at Helmholtz Zentrum Munich, at the Technical University of Munich…

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Fructose produces less rewarding sensations in brain

Fructose not only results in a lower level of satiety, it also stimulates the reward system in the brain to a lesser degree than glucose. This may cause excessive consumption accompanied by effects that are a risk to health, report researchers from the University of Basel in a study published in the scientific journal PLOS ONE. Various diseases have been attributed to industrial fructose in…

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Shunning the flu vaccine

Although receding since late March, the 2012-13 seasonal flu epidemic in metropolitan France, appears to be the longest in some 30 years, even if it did not strike the highest numbers, according to the monitoring network Sentinelles-Inserm.

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Tablets for the people?

Last week the English government closed its consultation on the effectiveness of vascular checks for high-risk people aged 40-74. Would this help? Experts from New Zealand and the WHO say "yes". Others argue that public health approaches targeting the whole population are both: cheaper and more effective than tablets.

Hoffnung für Patienten mit Arteriosklerose

Jede Behandlung mit einem Ballonkatheter provoziert die Narbenbildung an der Gefäßinnenwand, weil durch das Dehnen des verstopften Gefäßrohres mikrofeine Verletzungen entstehen. Unangenehme Folge sind erneute Verengungen der Arterien, weitere Gefäßweitungen werden nötig...Radiologen der Berliner Charité entwickelten nun einen Gefäßkatheter, der die Narbenbildung in den Gefäßwänden…

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Childhood obesity

Recent studies have shown that overweight and obesity during childhood and adolescence have a negative impact on the functioning of the internal walls of the arteries, paving the way to the development of an arteriosclerotic disease from an increasingly early age.

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Adolescent obesity - a major European concern

Computer games, TV, fast food, lack of exercise – what will be the medical consequences of rising obesity in the young and what can be done about it? Pernille Due, at the National Institute of Public Health, University of Southern Denmark in Copenhagen, studied 162,305 adolescents in 35 countries aged 11-15 years old.

E-health in the Netherlands

The Dutch E-health initiatives have made remarkable progress in recent years, writes Marcel Swennenhuis, President of Topicus HealthCare. Many solutions, such as online medication services, patient portals and web-based disease management initiatives, demonstrate the success of the country's EHR approach.

Winners of media prize announced

The International Chair on Cardiometabolic Risk (ICCR) is pleased to announce the three winners of the European Media Prize co-sponsored by the ICCR and the Association of European Journalists (AEJ) and launched in November 2007 to reward articles that best inform readers about a growing public health issue: abdominal obesity and related risk of cardiovascular disease.

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What wounds tell us

Every day, patients are admitted to surgeries, hospitals and outpatient clinics with chronic wounds. Careful inspection gives a wound therapist clues to the appropriate primary care required even before further diagnostic procedures are carried out. So what do the clinical signs and symptoms tell us? Report: Heidi Heinold

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EKF Diagnostics at AACC

First fully integrated chemistry system

EKF Diagnostics, the global in vitro diagnostics company, announced the international launch of the Altair™ 240 clinical chemistry analyzer at the American Association for Clinical Chemistry’s (AACC) Annual Meeting and Clinical Lab Expo in Atlanta. This new bench-top platform represents EKF Diagnostics’ first fully integrated chemistry system designed for the global market. Also EKF…

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Therapy

Approach to reverse kidney damage

Adults who are worried or terrified sometimes curl up into a fetal position. Likewise, adult cells that are injured, including genetic injury leading to cancer, initiate a process that was present during embryonic development.

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PlasmaDerm

Plasma makes wounds heal quicker

Many people suffer from skin disorders. Open wounds are a particularly acute problem, especially among the elderly. PlasmaDerm, a new medical technology solution, uses plasma to facilitate faster healing of wounds.

Tele-oncology proves successful in Canada

An estimated 6.7 million people in developed countries were diagnosed with cancer in 2007. Delivering their care is no easy matter. Tele-oncology, the remote provision of oncology services, could not only reduce the costs of consultations for cancer departments, but also for patients. Kerry Heacox, of i.t. Communications, reports on the success of remote consultations in Labrador and Newfoundland.…

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Efficient processes in the Finnish hospital HUS

The Hospital District of Helsinki and Uusimaa (HUS) is the biggest of 20 hospital districts in Finland. It provides specialised and university level health care services in and around city of Helsinki, with regional responsibility of 1.5 million people.

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Measures to contain obesity

The World Health Organisation (WHO) quotes figures that indicate there are over one billion overweight adults spread across the world, as of 2007, with at least 300 million of these defined as clinically obese (as defined by a BMI (body mass index) of 30).

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Peripheral artery disease

Treating poor blood circulation with injectable gel

Bioengineers and physicians at the University of California, San Diego have developed a potential new therapy for critical limb ischemia, a condition that causes extremely poor circulation in the limbs and leads to an estimated 230,000 amputations every year in North America and Europe alone to prevent the spread of infection and tissue death. The new therapy could prevent or limit amputations…

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MERS

First reported autopsy of patient with MERS provides critical insights

Since 2012, at least 1,500 individuals have developed Middle East respiratory syndrome (MERS), resulting in more than 500 fatalities. Only now are results being reported of the first autopsy of a MERS patient, which was performed in 2014. Not only do these findings, published in The American Journal of Pathology, provide unprecedented, clinically-relevant insights about how MERS progresses, they…

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Cancer cells poised for growth when opportunity knocks

Researchers have identified a mechanism that allows cancer cells to respond and grow rapidly when levels of sugar in the blood rise. This may help to explain why people who develop conditions in which they have chronically high sugar levels in their blood, such as obesity, also have an increased risk of developing certain types of cancer.

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Free

App to improve World’s cardiovascular health

Leading cardiologist Valentin Fuster, MD, PhD, has developed a free mobile application called “Circle of Health” to empower individuals around the globe to take action to comprehensively assess and enhance their daily overall heart health. Cardiovascular diseases are the number one cause of mortality in the world. Dr. Fuster has created “Circle of Health” for the daily promotion of…

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Revolution

3-D printed muscles

With 3-D printing revolutionising manufacturing, its healthcare potential is being explored for medical devices, prosthetics, dentistry and drug development. One area under the spotlight is the creation of artificial muscles using a 3-D printing system. Dr Fergal Coulter, who has played an important role in helping develop the technique, outlined the manufacturing process, which he invented for…

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Evolution

On the cusp of Medicine 4.0

In the world of technology, the term Industry 4.0 is already well known. Univ-Prof. Dr. rer. nat. Bernhard Wolf has reveals a comparable development in medicine. Smart systems and personalisation have enormous potential, the Professor for Medical Electronics at the Technical University of Munich is convinced.

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Discovery

Viruses flourish in guts of healthy babies

Bacteria aren’t the only nonhuman invaders to colonize the gut shortly after a baby’s birth. Viruses also set up house there, according to new research at Washington University School of Medicine in St. Louis. All together, these invisible residents are thought to play important roles in human health.

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Politics

Europe faces unprecedented threats

Two of the core tenets underpinning the European vision – the euro and the Schengen agreement – are coming under unprecedented threat through financial challenges and the impact of the refugee crisis across the continent. It is these critical issues that keynote speaker Professor Martin McKee will tackle during the opening plenary session at the European Health Forum in Gastein in…

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Neuroradiology

More freedom, more responsibility

She is a neuroradiologist, professor, researcher and now the Medical Director of the Department of Neuroradiology at Dresden University Hospital. Her objectives are ambitious – be it in patient care, research or teaching. Professor Jennifer Linn MD wants to increase the quality of care, drive breakthroughs in research, ignite enthusiasm in students for their future profession and last, but not…

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W.A.R. against wound infections

Prevention is better than a fight against an infected wound – but, to avoid a battle you must know your enemy – and the wound’s infection risk level. Unfortunately, there are no generally accepted definitions for those risk levels. Now, the introduction of a new clinical assessment score – named W.A.R. (wound at risk) – which makes standardised classification of ‘risky’ wounds…

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European cancer mortality predictions for the year 2011

There will be nearly 1.3 million deaths from cancer in Europe in 2011 according to predictions from a study published in the cancer journal, Annals of Oncology. The estimates, which have been reached after researchers used for the first time in Europe a new mathematical model for predicting cancer mortality, show a fall in overall cancer death rates for both men and women when compared to 2007.

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Quality is the route to improving healthcare

Changing for the better does not depend on the number of hospitals, physicians or beds you have; it’s about eliminating inefficiencies in the pathways of patient care. The organising principle for healthcare needs to be quality. ‘It is the one industry where quality is cheaper,’ emphasises Ari Darzi, renowned pioneer in minimally invasive and robotic surgery, holder of the Hamlyn Chair of…

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Eat for goals

The UEFA and the World Heart Federation, with the support of the European Commission, today launched the children's cookery book, "Eat for Goals!". Its message of a healthy lifestyle is conveyed by a multicultural group of 13 internationally renowned male and female football players, who share what they love to eat and give recipes for their favourite dishes.

New twelve-month data for Nevo stent

At 12 months the NEVO Sirolimus-eluting Coronary Stent has continued to demonstrate excellent safety and efficacy outcomes compared to Taxus Liberte according to new data presented today from the NEVO RES-I clinical trial. These results were presented as a late breaking trial at EuroPCR, the leading medical conference in Europe for physicians specializing in interventional cardiovascular…

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Predictive analysis

The USA’s healthcare system has awakened to the fact that electronically stored health patient data can save billions of dollars. Predictive analysis of ‘Big Data’ is a hot topic.The USA’s healthcare system has awakened to the fact that electronically stored health patient data can save billions of dollars. Predictive analysis of ‘Big Data’ is a hot topic.

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The ESPOIR Study

Professor Axel Haverich and team at the Clinic for Cardiothoracic, Transplant and Vascular Surgery in Hanover Medical School (MHH) have been carrying out research into decellularised heart valves for over 15 years. They trialled a procedure – initially in the laboratory and in animal experiments – which does not cause tissue rejection, is hoped to last a lifetime and, in the case of children,…

A niche with no lobby

Italy is a front runner in diabetic foot revascularisation. Among the country’s pioneers is Professor Roberto Gandini, at the Diagnostic Imaging and Interventional Radiology Department, University of Tor Vergata in Rome, who has developed and improved new technical options in peripheral vascular disease intervention, a technique that now saves about 92% of patients from major amputations due…

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Advancing POC diagnostics

Improvements in microfluidics and detection technologies are beginning to expand the range of point-of-care diagnostics beyond simple blood chemistry tests to sophisticated immuno-assays and molecular diagnostics. Though yet to see much adoption in European hospitals, these point-of-care (POC) diagnostics are coming into use in the USA, initially in emergency rooms and ICUs where fast results are…

Secret to Healing chronic wounds might lie in tiny pieces of silent RNA

Scientists have determined that chronic wounds might have trouble healing because of the actions of a tiny piece of a molecular structure in cells known as RNA. The Ohio State University researchers discovered in a new animal study that this RNA segment in wounds with limited blood flow lowers the production of a protein that is needed to encourage skin cells to grow and close over the sore.

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Procedure update

Endoscopy in Lithuania

The well-known Whipple procedure, or pancreaticduodenectomy, recently underwent a transformation due to the skills of Nerijus Kaselis MD, Head of Abdominal and Endoscopic Surgery at Klaipeda District Hospital.

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Cardiovascular disease

Europe - Every year, 4 million people die from cardiovascular disease (CVD) in Europe as a whole (as many as 800,000 of them under 65 years old) and, in the EU Member States, over 1.5 million people die annually from CVD.

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Network science

Discovering what causes diseases

Systems biology allows the mathematical visualisation through graphs and networks of complex body processes such as disease development. The aim is to improve understanding processes and triggers of diseases, so as to access and repair a damaged network. ‘We are still approaching this issue with a lot of naivety and underestimate the complexity of biological systems, and therefore of…

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Endurance athletes should be tested for fatal heart condition

Some athletes who take part in endurance exercise such as marathon running, endurance triathlons or alpine cycling can develop irregularities in their heartbeats that can, occasionally, lead to their sudden death. Evidence published in the European Heart Journal by Professor La Gerche and colleagues has shown that doctors who try to detect these arrhythmias by focusing on the left ventricle of…

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An international impact on immunoassay

Snibe, the Shenzhen New Industries Biomedical Engineering Company Ltd., is a leading Chinese biomedical technology company dedicated to developing and manufacturing clinical laboratory equipment and in vitro reagents. Founded 18 years ago and a growing force in the Chinese market, the firm is based in Shenzhen, China’s fourth largest city, situated in Guangdong Province.

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AACC emphasises preventive diagnostics

San Diego, California - 20,000 international physicians, scientists and other visitors travelled to the Annual Meeting & Clinical Lab Expo of the American Association for Clinical Chemistry (AACC) in July, and 750 exhibitors emphasised the increasing importance of this gathering

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The European Network for Cell Imaging and Tracking Expertise (ENCITE)

Since June 2009, the focus of research in the European Network for Cell Imaging and Tracking Expertise (ENCITE) has been on finding biomarkers to aid cell transplantation. Funded with €11 million from the European Commission (EC), this major project that runs until 2013, involves 10 countries. Their work is coordinated by the European Institute for Biomedical Imaging Research (EIBIR) network,…

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Gender medicine

The insight that psychological, social and environmental conditions affect a person’s health is insufficiently considered in medical training and in the every-day diagnosis and treatment of patients.

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EHFG 2011 - ‘There are too many unnecessary operations!’

Participants at European Health Forum Gastein 2011 (EHFG) agreed: the tendency in Germany and Austria is to operate far too soon (particularly for hip, knee and disc surgery), and many surgical interventions are unnecessary, posing a particular and increasingly urgent problem especially in industrialised countries. Hans-Christian Pruszinsky reports

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Obese patients in radiology - XXL challenges

Radiological services and equipment are not yet adapted to obese patients. The accuracy of current MRI, CT and Ultrasound is hindered by subcutaneous and intraabdominal fat. These modalities are crucial in diagnosing pathologies associated with obesity, including heart-related disease. Optimising imaging modalities will be a major challenge for radiology.

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Personalized medicine could help to save 100 billion Euros

Despite huge increases in spending over the last three decades, progress in dealing with the most frequent and burdensome diseases is appalling. The EU Flagship Pilot IT Future of Medicine (ITFoM) could remedy that. The flagship‘s investments of 1 billion euros in the course of the next decade are expected to save up to 100 billion euros per year in health expenditures in the future.

European Health Forum Gastein

600 international politicians, economists, scientists, NGOs and healthcare organisations will discuss the effects of the global economic crisis on European healthcare systems during this autumn's European Health Forum Gastein (EHFG).

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The growing need for ‘cloud’ computing

In June 2009, IBM introduced the industry’s first set of commercial cloud services. Based on two years of research and hundreds of client engagements, the IBM Smart Business ‘cloud’ portfolio aims to help clients turn complex business processes into simple services. How does IBM explain what cloud services are? Cloud Computing is a form of IT use where the end user can utilise…

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Neuropelveology

Forging links between neurology and surgery

Surgery in the lower pelvic region often involves injury to or severing of nerve tissue. As in chronic diseases of the nervous system, the result can be pain, sensory disturbances or loss of function. Up to now the poor view of the nerves, partially formed of fine interwoven networks, has been one of the major problems – exacerbated by the strict division of skills between neurologists and…

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Transplants

Cell-free DNA offers several advantages

As part of a national, joint research project in cooperation with Chronix Biomedical (San Jose, CA/USA/Göttingen/Germany), Professor Michael Oellerich MD is on new biomarkers in organ transplantation, aiming to develop personalised immunosuppression for patients. This also entails the development of molecular test procedures, among others for the early detection of rejection. The keyword here is…

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Strong international feedback gives “MedTech” industry tailwind for exports

Summing up results of the world’s biggest medical trade fair after four days (16 – 19 November 2011) Joachim Schäfer, Managing Director at Messe Düsseldorf, said: “The manufacturers of medical device technology, medical products and medical IT have once again used the framework of MEDICA in Düsseldorf to impressively evidence their operational excellence.

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POCT brings values

Bedside testing of parameters has been introduced in clinical practice much earlier than laboratory testing: In past centuries, not only were temperature or pulse rate taken at the point of care (POC), but also qualitative blood or urine analysis were performed right next to a patient’s bed

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Modern radiological diagnostics for the evaluation of muscle diseases

Muscular diseases belong to a heterogeneous group with various causes like neurogenic, metabolic, dystrophic, or inflammatory mechanisms as well as channelopathies leading to disorders of the muscle cell membrane potential. In most progressive disease cases the result is a focal or general muscle weakness that, unfortunately, is a very unspecific symptom. Standard neuromuscular literature…

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Swiss Army Knife for Laboratories

Liquid Chromatography Tandem Mass Spectrometry

During the past 15 years, liquid chromatography tandem mass spectrometry (LC-MS/MS) has evolved into a vital technology used to perform routine tests in many clinical laboratories. Historically, LC-MS/MS had been used primarily by research, pharmaceutical, or commercial laboratories; however, advances in the technology, decreasing costs for basic systems, intelligible software, an increased…